ID R0GCV0_9BRAS Unreviewed; 933 AA.
AC R0GCV0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CARUB_v10019740mg {ECO:0000313|EMBL:EOA33592.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA33592.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB870806; EOA33592.1; -; Genomic_DNA.
DR RefSeq; XP_006300694.1; XM_006300632.1.
DR AlphaFoldDB; R0GCV0; -.
DR STRING; 81985.R0GCV0; -.
DR eggNOG; KOG4658; Eukaryota.
DR OrthoDB; 704711at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1185; DISEASE RESISTANCE RPP8-LIKE PROTEIN 3-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 5..91
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 166..412
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 933 AA; 107515 MW; BE9635BB157F7198 CRC64;
MTDPIVSFGV QKLWELITQE YERLSGIREQ VTELKADLDI LMCFLTDADA RKQTTALARK
CVDEVKEITY DAEDIIETYL LKGERSESSG IKNYMKSLHF QFVRRDTAFE IASISKRISK
VVQVMRDFGI QSNIIEGGYS QFLQDRKREA RHTFSSEFEN NLVGLEKNVK RLAEELVEND
LSHGVSITGL GGLGKTTLAR QIFNHDTVKH HFDGLAWVCV SQDFTRKDVW QTILGNLSPG
DKESNLREDE IQKKLFHLLE TRKVLIVFDD LWKKEDWDRI KLMFPERKAG WKVLLTSRND
AIHPHCTTFK PELLIHDECW ELLQMIAFPK NDTTIGYKVD EEMIEMAKEM VKHCGRLPLA
IKLLGGLLAA QHTSHQWKLI SENIKSHILL GGVSSTVDDC SSVNYILSLS FEGLPSYLKQ
CLLYLASSPE DHRIILRRLS YVWAAEGMIK LRHYEGATIR DVADLYIEEL VMRNMVISER
DVETSRFENC QLHDLIREIC LLKAKEENFL QIVSDPTCSS NVHSQTSSKS RRLVIYVTQS
FNGESELKNS KLRSLLFIDV GNDIYMGSNF MKLLPLLRVL DLDYVKLKGG KLPSSIGKLI
HLKYLSLYMA EVTHLPSSLR NLKSLLYLNL DVRGKLTDVP NVFKEMLELR YLRLPELPHC
RTKLELGNLL NLERLHNFST MHSSVTDLHH MTRLRSLRIS GMWDVETLTS TLSRLEMLED
LTIIYVNQLK LPALQHIPSH LTTIYLSGCC LEEDPMPILE KLLQLKSVVL GLNSYVGRRM
DCSGRGFPQL QILKLDYLCE LEEWVVEEGS MPLLHTLIIK WCPKLKKLPL GQRFIIPKLQ
KLSIGFLKEL EEWIVEEGSM PLLHTLKIRN CDMLKELPDG LKYITSLKEL SIRTQEKELQ
KKVSKGGEDY YKIQHIPLLD YGWLPEPEEN EGN
//
