ID R0GI66_9BRAS Unreviewed; 329 AA.
AC R0GI66;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Pseudouridine synthase RsuA/RluA-like domain-containing protein {ECO:0000259|Pfam:PF00849};
GN ORFNames=CARUB_v10020638mg {ECO:0000313|EMBL:EOA35436.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA35436.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
RN [2] {ECO:0000313|EMBL:EOA35436.1}
RP NUCLEOTIDE SEQUENCE.
RA Schmutz J., Prochnik S., Nordborg M., Weigel D., Rokhsar D., Wright S.;
RT "Genome sequencing of Capsella rubella.";
RL Nat. Genet. 0:0-0(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a uridine in RNA = a pseudouridine in RNA;
CC Xref=Rhea:RHEA:48348, Rhea:RHEA-COMP:12068, Rhea:RHEA-COMP:12069,
CC ChEBI:CHEBI:65314, ChEBI:CHEBI:65315;
CC Evidence={ECO:0000256|ARBA:ARBA00000073};
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DR EMBL; KB870806; EOA35436.1; -; Genomic_DNA.
DR EMBL; KB870806; EOA35437.1; -; Genomic_DNA.
DR RefSeq; XP_006302538.1; XM_006302476.1.
DR RefSeq; XP_006302539.1; XM_006302477.1.
DR AlphaFoldDB; R0GI66; -.
DR STRING; 81985.R0GI66; -.
DR GeneID; 17895353; -.
DR KEGG; crb:17895353; -.
DR eggNOG; KOG1919; Eukaryota.
DR OrthoDB; 5479603at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR PANTHER; PTHR21600:SF47; RNA PSEUDOURIDINE SYNTHASE 1; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01129; PSI_RLU; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 84..272
FT /note="Pseudouridine synthase RsuA/RluA-like"
FT /evidence="ECO:0000259|Pfam:PF00849"
SQ SEQUENCE 329 AA; 36469 MW; 8A585B2B648F280B CRC64;
MSLLRNLFSF SFSANSIITK PYFAFSIKSM EATTSELNLN YPKPISSPPP PISKDIELKR
AMEASSKSSL YNLTRDDVLY EDEHLMAVNK PKGVYCEAVL RSAPQIVLDS SSEFHLANRL
DRDTSGVMII TKSHKVAAKL VKAFTEHKIR KSYIALCIGS SPNWSKVTVS SGHGRSKHGA
WRVYSALDVG RVLPGGSFVR DMETTFEVVS VNGVKSESCE VDGVKTESCE VESVVVVEGK
REVSSCEGDD VVVVVRAFPR SGRTHQIRLH CQYLGIPIRG DVKYHGRYEW CGRTFEGHEL
HAECLSLDHP VTDEPIVFRA PVPCWAAGD
//
