ID R0GJW8_9BRAS Unreviewed; 1780 AA.
AC R0GJW8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=CARUB_v10008079mg {ECO:0000313|EMBL:EOA36031.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA36031.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KB870805; EOA36031.1; -; Genomic_DNA.
DR RefSeq; XP_006303133.1; XM_006303071.1.
DR STRING; 81985.R0GJW8; -.
DR eggNOG; KOG0929; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR032817; Mon2_C.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF401; BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF16206; Mon2_C; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 601..788
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 44..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1326..1348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..584
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1329..1343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1780 AA; 198022 MW; A173FC310DA3573A CRC64;
MASTEVDSRL ARVVIPALDK VIKNASWRKH SKLAHECKSV IERLRSPDNS SPVADSDSGS
SIPGPLHDGG AAEYSLAESE IILSPLINAS STAVLKIVDP AVDCIQKLIA HGYVRGEADP
TGGPEALLLS KLIETICKCH ELDDEGLELL VLKTLLTAVT SISLRIHGDS LLQIVRTCYG
IYLGSRNVVN QATAKASLVQ MSVIVFRRME ADSSTVPIQP IVVAELMEPT DKSESDPSTT
QSVQGFITKI MQDIDGVFNS ANAKGTFGGH DGAFETSLPG TANPTDLLDS TDKDMLDAKY
WEISMYKSAL EGRKGELADG EVEKDDDSEV QIGNKLRRDA FLVFRALCKL SMKTPPKEDP
ELMRGKIVAL ELLKILLENA GAVFRTSDRF LGAIKQYLCL SLLKNSASNL MIIFQLSCSI
LLSLVSRFRA GLKAEIGVFF PMIVLRVLEN VAQPDFQQKM IVLRFLDKLC IDSQILVDIF
INYDCDVNSS NIFERMVNGL LKTAQGVPPG TVTTLLPPQE AAMKLEAMKC LVAVLRSMGD
WVNKQLRLPD PYSAKLLEID DRNLEEGSHP VENGKGDAGH GGFERSESQS ELSSGTSDAL
AIEQRRAYKL ELQEGISIFN QKPKKGIEFL IKANKVGDSP EEIAAFLKDA SGLNKTLVGD
YLGEREDLSL KVMHAYVDSF EFQGMEFDEA IRAFLRGFRL PGEAQKIDRI MEKFAERYCK
CNPKAFSSAD TAYVLAYSVI LLNTDAHNPM VKSKMTADGF IRNNRGIDDE KDLPEDYLRA
LYERISRNEI KMKDDGLGPQ QKQPTNSSRL LGLDTILNIV VPRRGDDMYM ETSDDLIRHM
QERFKEKARK SESVYYAASD VVILRFMVEV CWAPMLAAFS VPLDQSDDAV VTALCLEGFH
HAIHVTSVMS LRTHRDAFVT SLAKFTSLHS PADIKQKNIE AIKAIVKLAE EEGNYLQDAW
EHILTCVSRF EHLHLLGEGA PPDATFFAFP QTESGNSPLA KPNSVPAIKE RAPGKLQYAA
SAVIRGSYDG SGVAGKASNT VTTEQMNNLI SNLNLLEQVG DMSRIFTRSQ RLNSEAIIDF
VKALCKVSMD ELRSPSDPRV FSLTKIVEIA HYNMNRIRLV WSSIWLVLSD FFVTIGCSDN
LSIAIFAMDS LRQLSMKFLE REELANYNFQ NEFMKPFVVV MRKSGAVEIR ELIIRCVSQM
VLSRVDNVKS GWKSMFMVFD PSNFHICCCL SQFLVTDIRT ELCLFLQIFT TAAHDAHKNI
VFLSFEMVEK IIRDYFPHIT ETETTTFTDC VNCLVAFTNS KFEKDISLQA IAFLQYCARK
LAEGSVGSSL RRNPPSSPQG GKGGKQDSGK FLESDEHLYS WFPLLAGLSE LSFDPRAEIR
KVALKVLFDT LRNHGDHFSL SLWERVFESV LFRIFDYVRH DVDPSGEDSA DQRGYSGEVG
QESWLYETCS LALQLVVDLF VNFYKTVNPL LKKVLMLFVS LIKRPHQSLA GAGIAALVRL
MRDVGHQFSD EQWLEVVSCI KEAADATSPD FSYVTTEDLT EDVSNEDETN DNSNDALRRR
NRQLHAAVAD AKSKASVQIF VIQAVTDIYD MYRTSLTANH MLMLFDAMHG IASNAHKINA
DPLLRSKLQE LGSSPESQEA PLLRLENESF QTCMTFLDNL ISDQPVGYDE SKIETHLISL
CREVLEFYID ISCSKEQSSR WAVPSGSGKR KELTARAPLV VAAIQTLGNM GESLFKKNLP
ELFPLIATLI SCEHGSGEVQ VALSDMLQTS MGPVLLRSCC
//
