ID R0GNL4_9BRAS Unreviewed; 506 AA.
AC R0GNL4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CARUB_v10011646mg {ECO:0000313|EMBL:EOA37492.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA37492.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR EMBL; KB870805; EOA37492.1; -; Genomic_DNA.
DR RefSeq; XP_006304594.1; XM_006304532.1.
DR AlphaFoldDB; R0GNL4; -.
DR STRING; 81985.R0GNL4; -.
DR GeneID; 17899278; -.
DR KEGG; crb:17899278; -.
DR eggNOG; KOG1087; Eukaryota.
DR OrthoDB; 472902at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR PANTHER; PTHR45898:SF12; TOM1-LIKE PROTEIN 3; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 12..141
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 180..268
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 263..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 55462 MW; 755AAF6281C303BD CRC64;
MANNAAACAE RATNDMLIGP DWAINIELCD IINMEPSQAK EAVKVLKKRL GSKNSKVQIL
ALYALETLSK NCGESVYQLI VDRDILPDMV KIVKKKPDLS VREKILSLLD TWQEAFGGSG
GRFPQYYNAY NELRSAGIEF PPRTESSVPF FTPPQTQPII AQAAASDEDA AIQASLQSDD
ASALSMEEIQ SAQGSVDVLT DMLGALDPSH PEGINEELIV DLVEQCRTYQ RRVMTLVNTT
SDEALMCQGL ALNDNLQRVL QHHDDKAKGN SVPVTAPTPI PLVSINHDDD DESDDDFSQL
AHRSKRENAR GTGQGNFNPI LPPPPSSMRP VHVNSGAMDF LSGDVYKPQG TSESVKPPST
SQSSHLDSSA PVFDDPVPQR KSPEQAMFTK PVYDQTEQLP PAPWDTQEPR KYPPSMSART
NKRQEEYFQS TVPQQSSSGS ESSYDDLVGQ SRNLSLNPTA SAAAVTPPKK DDKPEDILFK
DLIEFAKTRT SSSSSSKPNN QNNKPF
//
