ID R0GUZ7_9BRAS Unreviewed; 725 AA.
AC R0GUZ7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=CSC1-like protein ERD4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CARUB_v10008433mg {ECO:0000313|EMBL:EOA39777.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA39777.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KB870805; EOA39777.1; -; Genomic_DNA.
DR RefSeq; XP_006306879.1; XM_006306817.1.
DR AlphaFoldDB; R0GUZ7; -.
DR STRING; 81985.R0GUZ7; -.
DR GeneID; 17899858; -.
DR KEGG; crb:17899858; -.
DR eggNOG; KOG1134; Eukaryota.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF100; CSC1-LIKE PROTEIN ERD4; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 641..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..170
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 192..352
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 363..635
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 725 AA; 82090 MW; 9C46C2E27DFBB642 CRC64;
MEFGSFLVSL GTSAVIFVVL MLLFTWLSRK SGNVSIYYPN RIIKGLEPWE GTSLTRNPFA
WMREAFTSSE QDIVNVSGVD TAVHFVFLST VLGIFACSGL LLLPTLLPIA ATDHNIKTRV
KNGTDTTSKG TFSQLDNLSM ANITKKSPRL WAFLGAVYWV SLVTYFFLWK AYKHVSTLRA
QALMSADVKP EQFAILVRDM PSPPDGQTQK EFIDSYFREI YPETFYRSLV MTENSKVNKI
WEKLEGYKKK LARAEAISAA TNNRPTNKTG MCGLVGKKVD SIEYYTELIN ESVAKLETEQ
KAVLAEKQQT AAVVFFTTRV AAASAAQSLH CQMVDKWTVT EAPEPRQLIW QNLNIKLFSR
ILRQYVIYFV VALTILFYMV PIAFVSAITT LKNLQKIIPF IKPVVDIAFI RTILESFLPQ
IALIVFLAML PKLLLFLSKS EGIPSQSHVI RAASGKYFYF SVFNVFLGVT LAGTLFNTVK
DIAKNPKLDM VINLLATSLP KSATFFLTYV ALKFFIGYGL ELSRIIPLII FHLKKKYLCK
TEAEVKEAWY PGDLSYQTRV PGDMLILTIT FCYSVIAPLI LVFGITYFSL GWLVLRNQAL
KVYVPSYESY GRMWPHIHQR ILAALFLFQV LMFGYLGAKT FFYTALVIPL IITSLIFGYV
CRQKFYGAFE HTALEVACRE LKQSPDLDEI FRAYIPHSLS THKAEEHEFK GAMSRYQDFN
AISAA
//
