ID R0H7B1_9BRAS Unreviewed; 773 AA.
AC R0H7B1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=CARUB_v10018495mg {ECO:0000313|EMBL:EOA25184.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA25184.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000256|ARBA:ARBA00038341}.
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DR EMBL; KB870809; EOA25184.1; -; Genomic_DNA.
DR RefSeq; XP_006292286.1; XM_006292224.1.
DR AlphaFoldDB; R0H7B1; -.
DR STRING; 81985.R0H7B1; -.
DR GeneID; 17884830; -.
DR KEGG; crb:17884830; -.
DR eggNOG; KOG1650; Eukaryota.
DR OrthoDB; 653151at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF152; CATION_H(+) ANTIPORTER 12; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..440
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 773 AA; 86235 MW; 1C2D964A4FAC84F4 CRC64;
MNTTTAYFNG CIPVVFNISS YGFWENLNSP DVIFEYSLPL MELQILLIFI FIIMIHIFLR
CIGTSPIPSY MLAGMILGPQ LFNLREISSG KLSWDPVLDG NAPLRGLSVC GNIMLAFLMT
VKISRRLAFH NGSLPIVIGI LTFIVPFFGG LCVRNLYMGS IDPYYLPHKK VIAERTVIIS
SQSSILLPTI TYFLSELKIL NSELGRLVLS ASLINDILGC FVSIVAYLGG TYKNVSPMTA
YRDLIAVIVL ILVVFFILRP VVEWIVESTP EGKPVADVYV HITVLSVIGS AAYSSFFNMK
YLLGPFFIGI IIPEGPPIGS ALEAKYEALT MNVLIPISIA FSTMRCDVMK IIYQFDDIIY
NIFLMVFTGV LKMAASMVPC LYCKVPFKEA IAASLLLCTK SFSEIFLYES TLDDSYISQA
TYTFLIICAL INSGIIPTAL EGLYDPKQKY IGYQKRSVMN LKPNSDLKIL TCVHKPENIS
MAISFLQLFP STIMVTVLHL VKLVGKIVPV LISHNKKTKQ LVNNSYILTA NLAFSQLESV
TMAMFTALTH ENLMHDEICK LALEQATSMI IIPSGRKWAI DGTFESEDEA MRRLNESLLK
NAPCSIGILM DRGQFSCKGT KRYHINVGLI FIGGKDDREA LSLVKKMKHN PRVKVTVIRL
ISNQEIETTN WDYILDHEVL EELINTEASN CIAYTERIVT GGPEVATMVR LLSEEYDLMV
LGRDHGTATP DFDGVKEWIE LPELGVIGDL LAAKDLDSRV SVLVVQQQQQ QQM
//
