ID R0H9W4_9BRAS Unreviewed; 525 AA.
AC R0H9W4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=DNA polymerase epsilon subunit {ECO:0000256|PIRNR:PIRNR000799};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|PIRNR:PIRNR000799};
GN ORFNames=CARUB_v10000704mg {ECO:0000313|EMBL:EOA20393.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA20393.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- FUNCTION: Participates in DNA repair and in chromosomal DNA
CC replication. {ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560, ECO:0000256|PIRNR:PIRNR000799}.
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DR EMBL; KB870810; EOA20393.1; -; Genomic_DNA.
DR RefSeq; XP_006287495.1; XM_006287433.1.
DR AlphaFoldDB; R0H9W4; -.
DR STRING; 81985.R0H9W4; -.
DR eggNOG; KOG3818; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR PIRSF; PIRSF000799; DNA_pol_eps_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR000799};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000799};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR000799};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 283..490
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
SQ SEQUENCE 525 AA; 59417 MW; 115601212774C5DA CRC64;
MSSTSQRKKI QKKFKNRGYN LKFDALDEIL VFADQFPDDA DGEAIDLLLD NLQESHESST
VDAESVRELI NRLLGAHNAP EEPTTSASSL AVIDAFLVPK FGYDAVKKKF NEHTKSLPIH
GEAYAKTALY RERFMLLSQR VSRAEHFSRP AFDAEMSQFE SNEISSIQSL ISQRGRKWVM
GVISQLEDGH FYLEDLSASV EIDLSKYKIT TGFFTENTII LAEGEMQVNG IFQVITCGFP
PLEDRDKTLK THSECDFFGG GTQTKEETIR LADLERQAVN DTFVILSDIW LDNEEVIGKL
ETVLDGFENV ETVPSLFVFM GNFCSRPCNL AFGSYSSLRE QFGKLGRMIG NHPRLKESSR
FLFIPGPDDA GPSTVLPRCA LPNYLTEELQ NIIPNAIFSS NPCRVKFYNQ EIVFFRQDLL
YRMRRSCLVT PSSEETKDPF KHLVYTITHQ SHLCPLPLMV QPIIWNYDHS LRLYPTPHTI
VLGDKSEQEV CKFGGTTCFN PGCFSTDSTF VAYRPSTQEV ELSAL
//
