ID R0HJ64_9BRAS Unreviewed; 1426 AA.
AC R0HJ64;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Enhancer of mRNA-decapping protein 4 WD40 repeat region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CARUB_v10012816mg {ECO:0000313|EMBL:EOA29729.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA29729.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the WD repeat EDC4 family.
CC {ECO:0000256|ARBA:ARBA00009639}.
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DR EMBL; KB870807; EOA29729.1; -; Genomic_DNA.
DR RefSeq; XP_006296831.1; XM_006296769.1.
DR STRING; 81985.R0HJ64; -.
DR eggNOG; KOG1916; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR Gene3D; 1.10.220.100; conserved c-terminal region of ge- 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045152; EDC4-like.
DR InterPro; IPR049404; EDC4_C.
DR InterPro; IPR044938; EDC4_C_sf.
DR InterPro; IPR032401; EDC4_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15598; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR PANTHER; PTHR15598:SF5; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR Pfam; PF21289; EDC4_C; 1.
DR Pfam; PF16529; Ge1_WD40; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 185..497
FT /note="Enhancer of mRNA-decapping protein 4 WD40 repeat
FT region"
FT /evidence="ECO:0000259|Pfam:PF16529"
FT REPEAT 232..274
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 351..393
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1297..1400
FT /note="Enhancer of mRNA-decapping protein 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21289"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..736
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 840..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..40
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..777
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..927
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1426 AA; 155263 MW; 4AD30666A2CF455A CRC64;
MASSPGNTNP HNPPPFDLGI LFKPSSNPYP APPASYPPPT GPFLHNQYDQ QHYALPAISA
QPSPVTQAQQ DVSSSSLATN LHPQRTLSYP TPPLNLQSPR SNHNPGTHIL ALLNNNNGGA
VANQEPSHQP PLVNHNEIAR SFPGGSGPIR VPSCKLPKGR RLIGEHAVYD VDVRLQGEIQ
PQLEVTPITK YGSDPQLVVG RQIAVNKVYI CYGLKGGNIR VLNINTALRS LFRGHSQRVT
DMAFFAEDVD MLASVSLDGK VFVWKISEGS EGDDQPQITG KIVCALQILG EQDTKHPRVC
WHCHKQEILV VSIGRHVLRI DTTKVGRGEV FSAEAPLQCP LDKLIDGVQI VGKHDGEVTD
LSMCQWMTTR LVSSSVDGTI KIWQDRKAQP LVVLRPHDGH PVSSATFVTS PERPDHIILI
TGGPLNREMK IWVSAGEEGW LLPADSESWR CTQTLALKSS TESRAEEAFF NQVIALSEAG
LLLLANAKRN ALYAVHLDYG NSPVETRMDY LSEFTVTMPI LSFIGTNDPP EEPIVKVYCV
QTLAIQQYTL DLSLCLPPPV ENMGLEKSDS NVSREANLVE STSEPSGLKP TDLPSVDSVP
KPSIIVNRSE SANKLSFTSA EATAQAIVPP NGEPKTSALP SETSGAGSAY ATSPKLPLSP
RLSRKLSGYH SPVDAIEPVT PHHELGGRAP SADYSVDRQM DAVGVSSCDV SSIEENSRSK
DPNVTPDDDL SGMRSPAAFF KHPTHLVTPS EILMGVSSAE ASTTNEDRRD RDANNFQDVN
NDARGAEVEV KEVSDTRSTQ NGETNDNDET ANRTSENREK VFCSQVSNLS TQMARDCYPS
TEGTFIPGES KAYGEPIQAG DESGLDTRGV SAKLPESGSS SGLQQSSAAN SKGKKQKAKN
SQGPSLSSSS SNLAESFNEQ RESLSHPMTD PLPQFLAMQE HESGDILILK PISTLFLTIS
VFILLHHSVI HYKICYYLDL AHKSSFILKQ KSVFVPNWQL SMIGYRFILR RTLIMASQKE
MQRQLSNAVT GPIVKESKRL EVALGRMIEK SSKSNADALW ARFQEETAKN EKALRDHSQQ
IVSATTNFMS KELNAMFEKT IKKELAAIGP ALARSVTPVI EKTVSSAITE SFQRGIGDKA
VNQLEKSVNL KLEATIARQI QAQFQTSGRQ ALQEALRSGL ESSVIPSFER ACKTMFDQMD
SAFQKGIAEH TNAAQQRLDS GHSQLAHTLR ETITSASSVA QALSRELAEN QRNFLALAAA
GANSGGSNPL ITQLSGGPLG ALLEKAEAPK DPTTELSRLI SERKYEESFT SALQRSDVSI
VSWLCSQVDL RGLLAMNPLP LSQGVLLSLL QQLACDISKD TSRKLGWMTD VVAAINPSDQ
MIAVHARPIF EQVYQILHHH RNAPGSDVSA IRLIMHVINS MLMGCK
//
