ID R0HSV7_9BRAS Unreviewed; 714 AA.
AC R0HSV7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=CARUB_v10016205mg {ECO:0000313|EMBL:EOA32889.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA32889.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; KB870807; EOA32889.1; -; Genomic_DNA.
DR RefSeq; XP_006299991.1; XM_006299929.1.
DR AlphaFoldDB; R0HSV7; -.
DR eggNOG; KOG0987; Eukaryota.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 550..596
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 714 AA; 80806 MW; 9B02E8BEED988364 CRC64;
MFLAWFELNK VSELARSLTY AQIPEYFTWD GKRKKFNLRK RPGSSIGRIN YVPISLEEGY
YLRVLLNTQT GPECFDDLKK VKGVVYKTFK EACFHLGLLD NDQEYIDDII RTSFWSTGNF
LRRLFVVMLQ SFSLSQAEIV WEKTWELLAE DIEKERREYY NRPELTLDDE EKKKYALLNI
DSILKSNGTS LKAFSTMPQI PEDSMDDTNV LILDEKNYDR QEQKEKHDKW VKQMTGEQKQ
IYEEIIEAVD NDMGGVFFVY GFGGTGKTFL YKTLSAALRS RGSIVLNVAS SGIASLLLAG
GRTAHSRFGI PINPHESSVC TICPGSDQAQ LVAEASLIIW DEAPMMSKHC FESLDRSLDD
IMKGDGKKPF GGKVVVFGGD FRQVLPIIPN AGRAEICMAA LNASYIWEHC KVLQLTKNMR
LLSTNLTTTE AKDLKDFSEW ILAVGDGRIA EPNDGEVMID IPEEFLITEA RNPIEAITRE
TYGDTKCWKD KTDPLFFQER AILCPTNEDV GIINEYMLDQ LEGEERTYLS SDSIDPADKR
AGNNPVLTPD FLNSLKVPGL PSHRIRLKVG CPVMLLRNID PRGGLMNGTR LQITQLAEFV
LEAIIITGDR VGDKVLIPRI LITPSDTKLP FKMRRRQLPL VVAFAMTINK SQGQSLDYVG
LYLPRPCFSH GQLYVAISRV TSKKGLKVLI VDKEGKPQKE TINVVFKEVF QNLG
//
