ID   R0HWH6_9BRAS            Unreviewed;      1012 AA.
AC   R0HWH6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CARUB_v10012885mg {ECO:0000313|EMBL:EOA29790.1};
OS   Capsella rubella.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX   NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA29790.1, ECO:0000313|Proteomes:UP000029121};
RN   [1] {ECO:0000313|Proteomes:UP000029121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX   PubMed=23749190; DOI=10.1038/ng.2669;
RA   Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA   Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA   Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA   Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA   Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA   Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT   "The Capsella rubella genome and the genomic consequences of rapid mating
RT   system evolution.";
RL   Nat. Genet. 45:831-835(2013).
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DR   EMBL; KB870807; EOA29790.1; -; Genomic_DNA.
DR   RefSeq; XP_006296892.1; XM_006296830.1.
DR   AlphaFoldDB; R0HWH6; -.
DR   STRING; 81985.R0HWH6; -.
DR   GeneID; 17891164; -.
DR   KEGG; crb:17891164; -.
DR   eggNOG; KOG2101; Eukaryota.
DR   OrthoDB; 2899602at2759; -.
DR   Proteomes; UP000029121; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06872; PX_SNX19_like_plant; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR003114; Phox_assoc.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR013937; Sorting_nexin_C.
DR   PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR   PANTHER; PTHR22999:SF23; SORTING NEXIN-16; 1.
DR   Pfam; PF08628; Nexin_C; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF02194; PXA; 1.
DR   SMART; SM00312; PX; 1.
DR   SMART; SM00313; PXA; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
DR   PROSITE; PS51207; PXA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          105..288
FT                   /note="PXA"
FT                   /evidence="ECO:0000259|PROSITE:PS51207"
FT   DOMAIN          530..642
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          379..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          736..757
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..413
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..446
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        447..469
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1012 AA;  115330 MW;  F8B32AA087D72DF1 CRC64;
     MKAMETIQDL IEEAKVRTVW WGLCIFSVTY LLTHTSKSMW MNLPMAILIL GVMRVLLNQI
     EFKWKVVPTP RQSQLSYPEK KQLSVKDARL SGIPPPPRWK KKIDSPVVEA AINDFIDKIL
     NDFVVNLWYS LITPDKEAPE LIRAVIMDAL GEISVRVKEI NIVDLLTRDI VDLIGDHLEM
     FRRNQAAIGI DVMKILSLEA RDERLKFHLM ASGELYPALV SPESEYKVLQ KIVAGILSVV
     LRPREAQSPL VRTIAREIVT CLVIQPLLNL ACPERINEVM EIIINLIKEG NFEQFTGEEQ
     NVNSAPLSAY DNQAKNMNLT KANEQKSPYV DERHPELHVQ QHSAGWAQLL EVATQRRTEV
     LTPENLENMW TKGRNYQKKE YKKSLKKGSS VSNSIEAKQD NQSSISRTSD GAKENAVAQL
     PPKASVDKQS QVQSAEEFSK SSSFKGGHHS YEADVRTESR SDGNKNRLKR SNSTSDLNLR
     PETSLALLAV SEGPIITEFY TTDFVKHNDN YRSDSNSPSI VLHKDGQQCL KLKCRVLGAY
     FEKLGSKSFA VYSIAVTDVE NKTWCVKRRY SNFERLHRQL KEIPNYNLQL PPKRIFSSST
     EDAFVHRRCI QLDKYLQDLL CIANVAEQHE VWDFLSEASK NYSFGKSSSV MKTLAVNVDD
     AMDDIVRQFK GVSGGLMRKV VGSPLEENDH APARHLSWSV NELNTQLSKE SATESIHSSF
     SDTEDIDKLE ENTQEEGRFD SEANGWHSDN ELNSKHFPPR VVRRLGEPEP SEKEIDFRAK
     SEVRGSTDMQ HPDPLTTLVP NPTGMPPEWN PPKVSVPILN LVDKVFQLNR RGWLRRQVFW
     ISKQILQLVM DDAVDDLLMR EICWLRNEDT VAQGIRWAQD ILWPNGVFFT RVNDSQEALD
     ETDPSEKTFQ MAGQLGGMKV AKPSSFEQQF EASRRSNEIK KFLFDGAPTA LVSLVGHNQY
     RRCARDIFYF TQSNVCIKQL TFAILELLLR SVFPELQDLL RDIRETSHGR SE
//