ID R0IB81_9BRAS Unreviewed; 771 AA.
AC R0IB81;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOA39719.1};
GN ORFNames=CARUB_v10008363mg {ECO:0000313|EMBL:EOA39719.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA39719.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KB870805; EOA39719.1; -; Genomic_DNA.
DR RefSeq; XP_006306821.1; XM_006306759.1.
DR AlphaFoldDB; R0IB81; -.
DR STRING; 81985.R0IB81; -.
DR GeneID; 17897098; -.
DR KEGG; crb:17897098; -.
DR eggNOG; KOG1134; Eukaryota.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF105; BNAC05G09770D PROTEIN; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 574..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..179
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 200..362
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 373..645
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 733..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 88424 MW; 3B051AB2900CB824 CRC64;
MATLEDIGVA ASINILTAII FLLAFAILRI QPFNDRVYFP KWYLKGIRSS PLHSGALVSK
FVNVDLGSYL RFLNWMPAAL KMPEPELIDH AGLDSAVYLR IYLTGLKIFV PVALLAWSIL
VPVNWTSDGL QLAKLRNVTS SDIDKLSISN IQRGSDRFWT HLVMAYAFTF WTCYVLMKEY
EKVAAMRLAF LQNEQRRPDQ FTVLVRNVPA DADESISESV EHFFLVNHPD HYLTHQVVYN
ANDLEALVEQ KKSTQNWLDY YQLKYTRNQE QRPRIKTGFL GLWGKNVDAI DHYIAEIEKL
NEQILEERKK VKKDDSSIMP AAFVSFKTRW GAAVCAQTQQ SSDPTEWLTE WAPEAREVFW
SNLAIPYVSL TVRRLIMHIA FFFLTFFFMI PIAFVQSLAS IEGIEKSAPF LKSIIDKKLV
KSVIQGFLPG IVLKLFLIFL PSILMVMSKF EGFVSLSSLE RRAAARYYVF NLVNVFLGSI
ITGSAFEQLD SFLKQSANQI PRTVGVAIPI KATFFITYIM VDGWAGIAGE ILRLKPLIFF
HIKNFFLVKT EKDREDAMNP GQINYHATEP RIQLYFLLGL VYAPVTPVLL PFIIIFFALA
YLVFRHQIIN VYNQEYESGA RFWPDVHGRI ISALMISQVL LMGLMSTKGA AQSTPFLLVL
PILTFFFHRF CKGRYEPAFL RHPLKEAMVK DTLEKARDPY FNLKPYLQKA YIHPVFRDDH
FEDSRFDEIS SYRAEDSDED CVTVPTKRQS RKNTPAPSHA SRGSSWSPPS K
//
