ID R0ILE9_9BRAS Unreviewed; 1179 AA.
AC R0ILE9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=CARUB_v10012033mg {ECO:0000313|EMBL:EOA37858.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA37858.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; KB870805; EOA37858.1; -; Genomic_DNA.
DR RefSeq; XP_006304960.1; XM_006304898.1.
DR AlphaFoldDB; R0ILE9; -.
DR STRING; 81985.R0ILE9; -.
DR GeneID; 17897645; -.
DR KEGG; crb:17897645; -.
DR eggNOG; KOG0351; Eukaryota.
DR OrthoDB; 1114285at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF153; ATP-DEPENDENT DNA HELICASE Q-LIKE 4A; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 450..625
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 650..809
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 665..706
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 1006..1088
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 301..328
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 220..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOA37858.1"
SQ SEQUENCE 1179 AA; 132506 MW; 87924D8D576F2257 CRC64;
RSYLPEVQKP IGPQTNWSEH AKALESPSSV TKFLSSNVLY ALESQKPRDM AARSISFPSV
NVHAHPQVTK AWRALSSLSI NNAYLRPGFT PPVDTSGTNG SYSARERSTV KVISSTDGSF
DRQNQSAMNV SGTGRSFHSF PSSVPGEDKI IAENFPRVNH EVRESEPRRT HLNGVENSFR
NSAFPSEQLE SGKACLDDID DDELLENIDV DQIVMEHYHS TSTPQPSASN FSLRTPPVDR
SASRFEEDGC MPSELCSNCS HGIKLGLCPE ASTHVDQMKD VLLAISNELL DDATDLSPDR
VQQLRQERLQ LKNQIQQLEN HIRDKDSRKS QFLSSTATHT FQYETPKSTT YKMDYPQTDF
RSLPSDQGRY VCDSWNMPRD SSFSVDKYGL SSAPVEREQY IPKIIDVTYT EGSSDKRWSS
HDFPWTRKLE INNKKVFGNH SFRPNQREII NATMSGSDVF VLMPTGGGKS LTYQLPALIC
PGITLVISPL VSLIQDQIMN LLQANIPAAS LSAGMEWAEQ LKIFQELNSE HSKYKLLYVT
PEKVAKSDSL LRHLENLNSR GLLSRFVIDE AHCVSQWGHD FRPDYQSLGI LKQKFPGIPV
LALTATATAS VKEDVVQALG LVNCIVFRQS FNRPNLWYSV VPKTKKCMED IDKFIKENHF
DECGIIYCLS RMDCEKVAEK LQEFGHKTAF YHGSMEPEQR AFVQTQWSKD EINIICATVA
FGMGINKPDV RFVIHHSLPK SIEGYHQECG RAGRDGQRSS CVLYYGYGDY IRVKHMISQG
GVDQSPMANG YNRVASSGRI LETNTENLLR MVSYCENEVD CRRFLQLVHF GEKFDSTNCK
NTCDNCCSTQ SLIDKDVTLI TKQLVELVKQ TGERFSSAHI LEVYRGSLNQ MVKKNRHETL
QLHGAGKHLS KIEVSRILHY LVTEDILVED VRKSDMYGSV SSLLKVNNTK ASLLFSGRQT
IMMRFPSSVK VVKPSKPGVT PAKGPLTSEK QSTLPLSTED APPKDLNLSA NMYTALRKLR
TALVKEAPDG VMAYHIFINS TLQQISRRIP RTKEELLEIN GLGKAKVSKY GDQLLETIES
TVNEYYGTNK KDSIISNDSP NSGKRRRDEN TSPNVAEDDD FEVSPSQSCK KTVRNKSNEV
LHGTCVDGDR VGMVMEKLDF DFEDEDGSEI RPEGRVLPW
//
