ID R0ILH1_9BRAS Unreviewed; 329 AA.
AC R0ILH1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=BFN domain-containing protein {ECO:0000259|PROSITE:PS51658};
GN ORFNames=CARUB_v10012529mg {ECO:0000313|EMBL:EOA39420.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA39420.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC Involved in basal defense response. Participates in abscisic acid-
CC derived callose deposition following infection by a necrotrophic
CC pathogen. {ECO:0000256|ARBA:ARBA00025428}.
CC -!- SIMILARITY: Belongs to the bifunctional nuclease family.
CC {ECO:0000256|ARBA:ARBA00009095}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB870805; EOA39420.1; -; Genomic_DNA.
DR RefSeq; XP_006306522.1; XM_006306460.1.
DR AlphaFoldDB; R0ILH1; -.
DR STRING; 81985.R0ILH1; -.
DR GeneID; 17899370; -.
DR KEGG; crb:17899370; -.
DR eggNOG; ENOG502QQ9S; Eukaryota.
DR OrthoDB; 304718at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.690.10; Bifunctional nuclease domain; 1.
DR InterPro; IPR036104; BFN_sf.
DR InterPro; IPR003729; Bi_nuclease_dom.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR15160:SF12; BIFUNCTIONAL NUCLEASE 2; 1.
DR PANTHER; PTHR15160; VON HIPPEL-LINDAU PROTEIN; 1.
DR Pfam; PF02577; BFN_dom; 1.
DR Pfam; PF02151; UVR; 1.
DR SUPFAM; SSF103256; Hypothetical protein TM0160; 1.
DR PROSITE; PS51658; BFN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT DOMAIN 121..256
FT /note="BFN"
FT /evidence="ECO:0000259|PROSITE:PS51658"
SQ SEQUENCE 329 AA; 36967 MW; A0E1E1CCCE42F151 CRC64;
MRSLQTPVVC PSVRPRQLGV SASLVNCSVS KPRILKNQFW GNETRNVKSQ VATVSLQLHL
RRCKSITCLF SSHSDGSGST AENFNENDED YVKSSVLEAV EVKSGPDGFM VKMRDGRQLR
CVHNNPQGGN LPNYAPHSAI VLKMEDGTGL LLPIIVLEMP SVLLMAALTN VQIARPTMYQ
VVTEMIDKMG YEVRLVRVTT RVHEAYFAEL YLSKVGDKSE CVSFDLRPSD AINIAVRCKV
PIQVNKYLAY SDGMRVIDSG KLSKQTPASD GLLFHELDRP NGQPCFDTKE FDLLRNMMQA
VNEERYDEAA EWRDKLGQFQ AKRKLKKYT
//
