ID R0JH74_ANAPL Unreviewed; 427 AA.
AC R0JH74;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cytotoxic and regulatory T-cell molecule {ECO:0000313|EMBL:EOA96326.1};
DE Flags: Fragment;
GN ORFNames=Anapl_06774 {ECO:0000313|EMBL:EOA96326.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA96326.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
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DR EMBL; KB744031; EOA96326.1; -; Genomic_DNA.
DR AlphaFoldDB; R0JH74; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR47118; CYTOTOXIC AND REGULATORY T-CELL MOLECULE; 1.
DR PANTHER; PTHR47118:SF1; CYTOTOXIC AND REGULATORY T-CELL MOLECULE; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..85
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 105..192
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 228..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOA96326.1"
FT NON_TER 427
FT /evidence="ECO:0000313|EMBL:EOA96326.1"
SQ SEQUENCE 427 AA; 47069 MW; 4B0A5D791D838BD9 CRC64;
LAGDFAEAGG ETVTLQEGED LNLSCTLRGS NSSVRQWLNP RGFTIFLDTK WGLRDQRYKL
IHYSEDELSI RLSNVTVHDE GVYKCFYYGT PFKVKTTTVE VLAAPSKPVL EASHDTERGI
TLSCSTRGSK PRPQITWLLD NGIQLPGDTT HKLEANGEKW TTTSTLTVLA YGPNSTASCL
VHHKALKEEK LAVPFRFEDL PGTVTNTYPA STAQEVVTHV SEHEQPTAIA TESDLDNSTD
FSPSYPQHNG PEATSAAAGE EELSGTPSHH VPNGTDTASN GTVIEDELPR TEASPPSENI
TQISIITFEQ DLLSEGIQRE KDVLLPSLVA VLIFVLLIIV VLFMRKLKKA HGVWKRENDN
SEQTLESYKS KSNEESPGHE KNEQAVNQKS NVQYVTEGYA EKPQKNPGEK NITIAEKLFT
CGRETDV
//
