ID R0JUA9_ANAPL Unreviewed; 716 AA.
AC R0JUA9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Leucine rich repeat neuronal 1 {ECO:0000313|Ensembl:ENSAPLP00020023124.1};
DE SubName: Full=Leucine-rich repeat neuronal protein 1 {ECO:0000313|EMBL:EOB01091.1};
DE Flags: Fragment;
GN ORFNames=Anapl_10954 {ECO:0000313|EMBL:EOB01091.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB01091.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|EMBL:EOB01091.1}
RP NUCLEOTIDE SEQUENCE.
RA Li N.;
RT "The genome sequence and transcriptome of duck provide insight into the
RT interaction host.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
RN [3] {ECO:0000313|Ensembl:ENSAPLP00020023124.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; KB743136; EOB01091.1; -; Genomic_DNA.
DR RefSeq; XP_005019963.1; XM_005019906.2.
DR Ensembl; ENSAPLT00020024963.1; ENSAPLP00020023124.1; ENSAPLG00020016071.1.
DR HOGENOM; CLU_000288_18_18_1; -.
DR OMA; KTTVRFM; -.
DR OrthoDB; 3968250at2759; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR Proteomes; UP000694400; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373:SF97; LEUCINE-RICH REPEAT NEURONAL PROTEIN 1; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01463; LRRCT; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..716
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014108610"
FT TRANSMEM 631..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 424..517
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 525..617
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 691..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 716
FT /evidence="ECO:0000313|EMBL:EOB01091.1"
SQ SEQUENCE 716 AA; 80931 MW; 350A0C1041B672B7 CRC64;
MAKIRLVLTV CQLVLELLMN SLTESSVQSN ECPQLCVCEI RPWFTPQSTY REATTVDCND
LRLTKIPSNL SSDTQVLLLQ SNNIAKTTDE LQQLFNLTEL DFSQNNFTSI KDVGLSNLTQ
LTTLHLEENQ ITEMTDYCLQ DLCNLQELYI NHNQISSISA NAFSGLKNLL RLHLNSNKLK
VIDSRWFDST PNLEILMIGE NPVIGILDMN FKPLSNLRSL VLAGMYLTDI PGNALVGLDS
LESLSFYDNK LVKVPQLALE KVPNLKFLDL NKNPIHKIQE GDFKNMLRLK ELGINNMGEL
VSVDRYALDN LPELTKLEAT NNPKLSYIHR LAFRNVPALE SLMLNNNALN AVYQKTVESL
PNLREISIHS NPLRCDCVIH WINSNKTNIR FMEPLSMFCA MPPEYRGQQV KEVLIQDSNE
QCLPMISHET FPNHLNLDIG MTVFLDCRAM AEPEPEIYWV TPLGNKVTVE SLSDKYKLSS
EGTLEISNIQ IEDSGRYTCV AQNIEGADTR VATIRVNGTL LDGTQVLKIY VKQAESHSIL
VSWKVNSNVM TSNLKWSSAT MKIDNPHITY TARVPVDVHE YNLTHLQPST DYEVCLTVSN
IHQQTQRSCV NVTTKNAAFA LDISDQETST ALAAVMGSMF AVISLASISV YIAKRFKRKN
YHHSLKKYMQ KTSSIPLNEL YPPLINLWEG DSEKDKDGSA ETKPTQVDTS RSYYMW
//
