ID R0JZ51_ANAPL Unreviewed; 459 AA.
AC R0JZ51;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
DE Flags: Fragment;
GN ORFNames=Anapl_13109 {ECO:0000313|EMBL:EOB02876.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB02876.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR EMBL; KB742922; EOB02876.1; -; Genomic_DNA.
DR AlphaFoldDB; R0JZ51; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:EOB02876.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049}.
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 224..251
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 22..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB02876.1"
FT NON_TER 459
FT /evidence="ECO:0000313|EMBL:EOB02876.1"
SQ SEQUENCE 459 AA; 50957 MW; 14FE5BA6A8813180 CRC64;
PAVTPHPSSS PPLADGPNDG EKPTGGKSKA ELRAERRAKQ EAERAQKQAK KAELGQAAPP
AKPRLTPTEP PTVVKRLPEH VQVDDPAALR KLAKKLERQQ VPLRQDYGTK VNLFSHLHQY
SRKKPLTQQM SIPSTVIHPA VVRLGLQYSQ GIINGSNARC IALLEVFKQL IRDYATPPNE
ELSRDLVAKL KPHISFLNQC RPLSVSMGNA IKFLKKEISC LPDTLREEEA KEKLQSTIDN
YLREKIVLAA EAISKSAFEK INDRDVILVY GCSSLVNRTL CDAHMQKGRA FRVIVVDSRP
RLEGRETLRR LVRKGIHCTY VMINAISYVL PEVSKVLLGA HALLANGSVM SRVGTSQIAL
VSKAYNVPVL VCCETYKFCE RVQTDSFVSN ELDDPDDLIV LRKGQAQLGG WSENKSLRLL
NLVYDVTPPD LVDLVITDLG MIPCTSVPVV LRVKNVDQQ
//
