ID R0KR83_NOSB1 Unreviewed; 553 AA.
AC R0KR83;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
DE Flags: Fragment;
GN ORFNames=NBO_376gi002 {ECO:0000313|EMBL:EOB12722.1};
OS Nosema bombycis (strain CQ1 / CVCC 102059) (Microsporidian parasite)
OS (Pebrine of silkworm).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae; Nosema.
OX NCBI_TaxID=578461 {ECO:0000313|EMBL:EOB12722.1, ECO:0000313|Proteomes:UP000016927};
RN [1] {ECO:0000313|EMBL:EOB12722.1, ECO:0000313|Proteomes:UP000016927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQ1 / CVCC 102059 {ECO:0000313|Proteomes:UP000016927};
RX PubMed=23496955; DOI=10.1186/1471-2164-14-186;
RA Pan G., Xu J., Li T., Xia Q., Liu S.L., Zhang G., Li S., Li C., Liu H.,
RA Yang L., Liu T., Zhang X., Wu Z., Fan W., Dang X., Xiang H., Tao M., Li Y.,
RA Hu J., Li Z., Lin L., Luo J., Geng L., Wang L., Long M., Wan Y., He N.,
RA Zhang Z., Lu C., Keeling P.J., Wang J., Xiang Z., Zhou Z.;
RT "Comparative genomics of parasitic silkworm microsporidia reveal an
RT association between genome expansion and host adaptation.";
RL BMC Genomics 14:186-186(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
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DR EMBL; KB909284; EOB12722.1; -; Genomic_DNA.
DR AlphaFoldDB; R0KR83; -.
DR STRING; 578461.R0KR83; -.
DR EnsemblFungi; EOB12722; EOB12722; NBO_376gi002.
DR VEuPathDB; MicrosporidiaDB:NBO_376gi002; -.
DR HOGENOM; CLU_001485_2_1_1; -.
DR OMA; KNTTHRE; -.
DR Proteomes; UP000016927; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR PANTHER; PTHR47969:SF15; ZGC:66125; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000016927}.
FT DOMAIN 4..298
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 406..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 71..78
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
FT NON_TER 553
FT /evidence="ECO:0000313|EMBL:EOB12722.1"
SQ SEQUENCE 553 AA; 62264 MW; EF8392DEBF508416 CRC64;
MNSKINVEIR IKPSIENTID SNSKSLTVGT KTYNFDKVHL TTSQKQLYTS SIEPLLSKFI
EGYNCSVLAY GQTGSGKTYT MGISELDTSG IVPQSLEYLF RNLNEKSLTC TFIEIYNEEV
IDLLSSHKVP LSLREIKGEV HVAGANEVNL NSVEEGLDVL RRGCRERTTK STKMNSQSSR
SHAIFTLFLR RESRGLFISS KFSFVDLAGS ERLKRTLCIG ERARESISIN SGLLALGNVI
SALYKKAKHV PFRDSKLTRI LHSCLNGHVL MIACISSSQS DMNETHNTLK YANRAASIQT
ATKLNVEVDN TKMVVILLKK EISKLKTENQ ILKSRIQTTK HANVEGLIRE NRLLKSQIEN
IKYDTLIDEK NEDLAQEILK HPFVQNLIND NQKLTEEVER LKGEVKDKAM DKSPPCPKVS
PLSLTNRPKV ISPSYQNELK NTPILSKATS PSCSPPFTKP IPKAPLTSKD PACLRTTSPV
LNTPPRSKTS PSEKISWNPS KQRKVTFKLE DQHNRRTLFT PRKEKVELNT DIIRSIEGYT
AQFMAIRDDH LIF
//
