ID R0L5A5_ANAPL Unreviewed; 326 AA.
AC R0L5A5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Tropomyosin 1 {ECO:0000313|Ensembl:ENSAPLP00020019943.1};
DE SubName: Full=Tropomyosin alpha-1 chain {ECO:0000313|EMBL:EOA95417.1};
DE Flags: Fragment;
GN Name=TPM1 {ECO:0000313|Ensembl:ENSAPLP00020019943.1};
GN ORFNames=Anapl_02698 {ECO:0000313|EMBL:EOA95417.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA95417.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|EMBL:EOA95417.1}
RP NUCLEOTIDE SEQUENCE.
RA Li N.;
RT "The genome sequence and transcriptome of duck provide insight into the
RT interaction host.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
RN [3] {ECO:0000313|Ensembl:ENSAPLP00020019943.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB744306; EOA95417.1; -; Genomic_DNA.
DR Ensembl; ENSAPLT00020021550.1; ENSAPLP00020019943.1; ENSAPLG00020012485.1.
DR OrthoDB; 5398117at2759; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR Proteomes; UP000694400; Chromosome 12.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.20.5.370; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR000533; Tropomyosin.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF41; TROPOMYOSIN 1; 1.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 2.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049}.
FT REGION 13..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 326
FT /evidence="ECO:0000313|EMBL:EOA95417.1"
SQ SEQUENCE 326 AA; 37652 MW; F6BAF9FCD2C6491F CRC64;
MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEERSKQLE DDIVQLEKQL HVTEDTRDQV
LEELHKSEDS LLSAEENAAK LEDELVALQK KLKGTEDELD KYSESLKDAQ EKLELADKKA
TDAESEVASL NRRIQLVEEE LDRAQERLAT ALQKLEEAEK AADESERGMK VIENRAQKDE
EKMEIQEIQL KEAKHIAEEA DRKYEEVARK LVIIESDLER AEERAELSES KCAELEEELK
TVTNNLKSLE AQAEKYSQKE DKYEEEIKVL TDKLKEAETR AEFAERSVTK LEKSIDDLEE
KVAHAKEENL NMHQMLDQTL LELNNM
//
