ID R0L652_ANAPL Unreviewed; 386 AA.
AC R0L652;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=T-box transcription factor T {ECO:0000256|ARBA:ARBA00040703};
DE AltName: Full=Brachyury protein {ECO:0000256|ARBA:ARBA00041469};
DE AltName: Full=Protein T {ECO:0000256|ARBA:ARBA00042501};
DE Flags: Fragment;
GN ORFNames=Anapl_19110 {ECO:0000313|EMBL:EOA95757.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA95757.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR EMBL; KB744190; EOA95757.1; -; Genomic_DNA.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20192; T-box_TBXT_TBX19-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 2.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR002070; TF_Brachyury.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF83; T-BOX TRANSCRIPTION FACTOR T; 1.
DR Pfam; PF00907; T-box; 2.
DR PRINTS; PR00938; BRACHYURY.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..170
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOA95757.1"
FT NON_TER 386
FT /evidence="ECO:0000313|EMBL:EOA95757.1"
SQ SEQUENCE 386 AA; 42070 MW; ADAC0131A81C3A23 CRC64;
AGESELRAGS EKGDPTEREL RVSLEEGELW LRFKEXAVPP VSPRRRMFPV LKVSVSGLDP
HAMYSFLLDF VXCVYIHPDS PNFGAHWMKA PVSFSKVKLT NKLNGGGQIM LNSLHKYEPR
IHIVRVGGPQ RMITSHSFPE TQFIAVTAYQ NEEITALKIK YNPFAKAFLD AKERSDHKDM
MEEVGDNQQS GYSQLGSWLI PGTGTLCPPA NPHPQFGAPL SLSPAHSCER YSSLRNHRSA
PYPNPYTHRN NSPTAYADNS SACLSMLQSH DNWSTLGVPT HTTMLPMSHS TGTATGSSQY
PNLWSVSNST ITPVSQSSGM SNGLSSQFLR GSPAHYSALP HPVAATASAS PLYDGGAPAD
LPDSQYDASA HARLASTWTP VTPPSM
//
