ID R0L8D5_ANAPL Unreviewed; 748 AA.
AC R0L8D5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=LIM domain-binding protein 3 {ECO:0000313|EMBL:EOA96557.1};
DE Flags: Fragment;
GN ORFNames=Anapl_04314 {ECO:0000313|EMBL:EOA96557.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA96557.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, Z line
CC {ECO:0000256|ARBA:ARBA00004216}.
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DR EMBL; KB743944; EOA96557.1; -; Genomic_DNA.
DR AlphaFoldDB; R0L8D5; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09454; LIM1_ZASP_Cypher; 1.
DR CDD; cd09362; LIM2_Enigma_like; 1.
DR CDD; cd09460; LIM3_ZASP_Cypher; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR031847; PDLI1-4/Zasp-like_mid.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR006643; Zasp-like_motif.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24214:SF9; LIM DOMAIN-BINDING PROTEIN 3; 1.
DR PANTHER; PTHR24214; PDZ AND LIM DOMAIN PROTEIN ZASP; 1.
DR Pfam; PF15936; DUF4749; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00132; LIM; 3.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00735; ZM; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 4.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1..84
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 570..628
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 629..688
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 689..748
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 164..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 748
FT /evidence="ECO:0000313|EMBL:EOA96557.1"
SQ SEQUENCE 748 AA; 81457 MW; E5E43BF8CAB52154 CRC64;
MAYNVTLNGP GPWGFRLQGG KDFNMPLTIS RITPGSKAAQ SQMNQGDLVV AIDGVNTDSM
THLEAQNKIK SANYNLSLTL QKSKRPVPVS TTAPKIDSPR AVIPHQKEPA WEINDNRTTF
SPLTNTATGP MGSVLATNGT FSGYLNKQEI SFSNSSSYLK TTTVRSSMSS QSVTPDISPA
KSNLGSKLSP ALADGNSPVH QLSPARQYNN PIGLYSAETL REMAEMHKLS LRRRASEGGL
PRGTEFTERF NPNVLKDSAL STHKPIEVKG LGGKATIIHA QYNTPISMYS QDAIMDAIAG
QAQAQGGEFA GTLPIKDPHV DSASPVYQAV LKTQNKPEDE TEDWGRRSAN LQSKSFRILA
QMTGTEYMQD PDEEALRRSR NTTQSYTPMP VSASYGESPA ASAASKPRVI TTASIKPSVY
QPVFDYAHGK EFFLMPSLSL PWCSLVPSLC PAISDQGAET STSLCAAPKG SCNEKFEMYA
PAPVHSYTPA NTEPASRPPW VTDDSFSQKF APGKTTTTVT KNILPRGAPV PSPASTPAYP
SPVSASSQAP AIARGTIQRA ERFPASSRTP LCGHCNSIIR GPFLVAMGRS WHPEEFNCAY
CKTSLADVCF VEEQNSVYCE RCYEQFFAPT CARCHTKIMG EVMHALRQTW HTSCFVCAAC
KKPFGNSLFH MEDGEPYCEK DYIALFSTKC HGCDFPVEAG DKFIEALGHT WHDTCFICAV
CHVNLEGHPF YSKKDKPLCK KHAHAINV
//
