ID R0LHU9_ANAPL Unreviewed; 417 AA.
AC R0LHU9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Alpha-1-antiproteinase {ECO:0000313|EMBL:EOA99912.1};
DE Flags: Fragment;
GN ORFNames=Anapl_03302 {ECO:0000313|EMBL:EOA99912.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA99912.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR EMBL; KB743257; EOA99912.1; -; Genomic_DNA.
DR RefSeq; XP_005021518.2; XM_005021461.2.
DR AlphaFoldDB; R0LHU9; -.
DR SMR; R0LHU9; -.
DR GeneID; 101803572; -.
DR KEGG; apla:101803572; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19548; serpinA_A1AT-like; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR Gene3D; 2.10.310.10; Serpins superfamily; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF385; SERPIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..417
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004344384"
FT DOMAIN 57..413
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT NON_TER 417
FT /evidence="ECO:0000313|EMBL:EOA99912.1"
SQ SEQUENCE 417 AA; 47155 MW; B7ADA4152BF74FA0 CRC64;
MKTDFYVYLL LAGLYTVAPG QLVTRHHDPN EPKDHVHYAG EAIACLKLVP NNADFAFHFF
NKVTLEEPNK NIFFSPVSIS TAFAMLALGA RSTTQTQILE GLAFNLTEIQ EKEIHEGFHN
LIHMLSHPES GVQLNMGSAI FLTEKLKPLK KFLDDAKALY QLETLTTNFN NPTEAEKQIN
DYIEKKTHGK ITNLVKEMDP QTVMLLATFV FFRGNWEKPF KPENTEEREF FVDAETIVKV
PMMYQTGRFD LYFDMELSCT VVRLHYNGSA TAFLVLPAKG KMKQLEQALV KETIREWSDR
LLQSKMRLYF PKFSISGSYE ITNILSKMGI VDVFTDRADL SGITGAPELK VSKVVHKAAL
DVDERGTEAA AATAAEIMTM SLPPTIEFNR PFLMLIFDRD TNSTLFIGKI VNPTITS
//
