ID R0M809_NOSB1 Unreviewed; 384 AA.
AC R0M809;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 03-MAY-2023, entry version 22.
DE SubName: Full=Vacuolar transporter chaperone 4 {ECO:0000313|EMBL:EOB14139.1};
GN Name=VTC4 {ECO:0000313|EMBL:EOB14139.1};
GN ORFNames=NBO_37g0014 {ECO:0000313|EMBL:EOB14139.1};
OS Nosema bombycis (strain CQ1 / CVCC 102059) (Microsporidian parasite)
OS (Pebrine of silkworm).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae; Nosema.
OX NCBI_TaxID=578461 {ECO:0000313|EMBL:EOB14139.1, ECO:0000313|Proteomes:UP000016927};
RN [1] {ECO:0000313|EMBL:EOB14139.1, ECO:0000313|Proteomes:UP000016927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQ1 / CVCC 102059 {ECO:0000313|Proteomes:UP000016927};
RX PubMed=23496955; DOI=10.1186/1471-2164-14-186;
RA Pan G., Xu J., Li T., Xia Q., Liu S.L., Zhang G., Li S., Li C., Liu H.,
RA Yang L., Liu T., Zhang X., Wu Z., Fan W., Dang X., Xiang H., Tao M., Li Y.,
RA Hu J., Li Z., Lin L., Luo J., Geng L., Wang L., Long M., Wan Y., He N.,
RA Zhang Z., Lu C., Keeling P.J., Wang J., Xiang Z., Zhou Z.;
RT "Comparative genomics of parasitic silkworm microsporidia reveal an
RT association between genome expansion and host adaptation.";
RL BMC Genomics 14:186-186(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB908945; EOB14139.1; -; Genomic_DNA.
DR AlphaFoldDB; R0M809; -.
DR STRING; 578461.R0M809; -.
DR EnsemblFungi; EOB14139; EOB14139; NBO_37g0014.
DR VEuPathDB; MicrosporidiaDB:NBO_37g0014; -.
DR HOGENOM; CLU_719792_0_0_1; -.
DR OMA; DEWHRAD; -.
DR Proteomes; UP000016927; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR InterPro; IPR003807; DUF202.
DR InterPro; IPR018966; VTC_domain.
DR InterPro; IPR042267; VTC_sf.
DR PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR PANTHER; PTHR46140:SF1; VACUOLAR TRANSPORTER CHAPERONE 4; 1.
DR Pfam; PF02656; DUF202; 1.
DR Pfam; PF09359; VTC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016927};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..185
FT /note="VTC"
FT /evidence="ECO:0000259|Pfam:PF09359"
FT DOMAIN 283..344
FT /note="DUF202"
FT /evidence="ECO:0000259|Pfam:PF02656"
SQ SEQUENCE 384 AA; 43889 MW; 3BF4E05B33901151 CRC64;
MNGEDVYSKV KEINKENVRD LYEEIQFTII KLKLKPVVRT FYKRQAYQLK NNNKVRISID
TDLCMIKEKI KENGEGLIEW RRGENNSKGG GCSSKEYGGG YYDKDGYYDT GSFTTNQPPS
HPPTYTPFPD LKKDQIVRFP YAILEIKTQG DYDSKPEWIT DLVEGPLVEH VHKFSKFLHG
CAVLYPFINE IPYWLPQVTK SIKKDPFDSE EITNKESEEG LYYDESNARG SPSQTHYINI
PSNNDNIPPN HNNIPPFIDD SDKLSPIDTH GKKIAIPVRV EPKVFFANER TFLSWVQFAI
FLGGIGTALL GMKEGTSSKM PGVLLIGVSI IFSFYALYLY LWRAGMIRKR HPGPYDDIYG
PPVLVVVFLI AMGLSIIYKF PLKK
//
