ID R1CBT1_EMIHU Unreviewed; 1128 AA.
AC R1CBT1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51192};
GN ORFNames=EMIHUDRAFT_117839 {ECO:0000313|EMBL:EOD19812.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD19812.1};
RN [1] {ECO:0000313|EMBL:EOD19812.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD19812.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD19812}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB866188; EOD19812.1; -; Genomic_DNA.
DR RefSeq; XP_005772241.1; XM_005772184.1.
DR STRING; 2903.R1CBT1; -.
DR PaxDb; 2903-EOD19812; -.
DR EnsemblProtists; EOD19812; EOD19812; EMIHUDRAFT_117839.
DR GeneID; 17265358; -.
DR KEGG; ehx:EMIHUDRAFT_117839; -.
DR eggNOG; KOG0947; Eukaryota.
DR HOGENOM; CLU_279455_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF13306; LRR_5; 2.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 480..644
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 671..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1106..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 856..883
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1128 AA; 119046 MW; 3D621B15696982CC CRC64;
MSANDHPSRE AALYHPWTVG SPADGWQVTI TAGHATLPDG LTHLSSRAFL ECKSLASVTC
PSSLVSIGDR AFDGCTSLAS IQLPDGLTSV GRHAFDGCSS LASIELPAGL ALVGAYAFRY
CASLASLSLP PALCCVEVGA FYCCSSLSSV TLPASLVSIG TAAFDGCSSL ASLPLPAGLA
SIGTLLSAGC FGLPPLLFTP RTTGHRQPLL PLLLLPHLRL TYLGKTAFYY CTSLASVAIP
DGVGLPLRPL PATAVSSIGP GCFRDCSSLA ELRLPSSLSP DAKHKSNHHS PLFRAALDQR
SRGHDLDGTA EMVKLVAFCP TTTVLRLSPA RMRAQERLRL LYQGVLAYKR CRPLLLGWLE
RAQIRLDSYG LDGGSVMTPL ACAYPVETHW FNTSVDHFNF RHAHGADPGG TFPLRFSHHG
PPADPGGTFP LRYLVHAQQW DGTAELLPRL VDGCAAGEPL ASLLPRCFDH PLDGFQTDAM
AALLDGSSVV VSAPTGSGKT AVAELALYAA LARGERAIYT TPLKALSNQK YRDLSAALGP
GSVGLLTGDT QKQRDAPVLV MTTEVLRNML LEQDEMVFAA QAAGRVGVVI LDEFHYMNDK
SRGTVWEECC VLAPPSAKLV ALSATMANAR QVTRWLEAIH GPTSLVETSH RPVPLRYRYA
DDLGVEDLFT SPAAGPGGGG GRGGGWRGGG GWADPRAQAR SEIAPVPSLL RELSHKAMLP
AIVFIFSRAG CDAAAEQAAA LRTPLVGAHE VGRIESIVAD FKRANGALLD SLDARLLARP
ADPIESNFCL GYGSALKLRR RRPLSECESL IARSFGAYTA RAKAETAVAQ LGGVEEERRR
LRALLARFDR SSVASYAKLQ GRLEAEQRSL SFLRAQEAEA EAEMVETLLG FVNRGTPART
SDGAAAIVAD DPPPAIAAAM RKAAAAAAGG AARPPPPRGR ATEFGALVAS LSGENELWLA
LVLMEAAAAE LEPPQLAAVL AATLDERLRP NTFVRFAPSE AVYETVDVLA DRAAELQRAQ
MAAGLSFPVG LDAGLCGLVE AWAAGEGWES LVAGTSLDLG DLFRLLRRSL ELLKTVSAVP
YVSEAAKAAA RAAVRACDRY PIAEDELMAL PEEEPGGGEE PGEARGGA
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