ID R1CIZ3_EMIHU Unreviewed; 1332 AA.
AC R1CIZ3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EMIHUDRAFT_430467 {ECO:0000313|EMBL:EOD22497.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD22497.1};
RN [1] {ECO:0000313|EMBL:EOD22497.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD22497.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD22497}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; KB865709; EOD22497.1; -; Genomic_DNA.
DR RefSeq; XP_005774926.1; XM_005774869.1.
DR STRING; 2903.R1CIZ3; -.
DR PaxDb; 2903-EOD22497; -.
DR EnsemblProtists; EOD22497; EOD22497; EMIHUDRAFT_430467.
DR GeneID; 17268043; -.
DR KEGG; ehx:EMIHUDRAFT_430467; -.
DR eggNOG; KOG1939; Eukaryota.
DR HOGENOM; CLU_002157_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 65..276
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 296..604
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 619..779
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 804..1321
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
FT REGION 709..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1332 AA; 139458 MW; 4F335510FFA29276 CRC64;
MEESERDVAK RRISKRNVER LRAFRDKGEL KQSLVSALAA ASSDGAASGD AGGGGAEGRN
ASGFRFSIDR GGTFTDVYAL CPGEAVPRCV KLLSVDPANY PDAPREGIRR VLEAATGVPH
PRGERLNSSR IEWIRMGTTV ATNALLERDG ARTALLVSKG FADVLHIGSQ ARPDIFDLRV
RCPGVLYEAV VEVDERVVLA KSEPPGEESA ARRGLRRVRG ETGEQVLIER EPDLDALRGK
LAALRASGVE AVAVVLMHAY TYRQHEEAVA ALAREVGFAQ VTTSSSTLPM VKLVPRGYTA
TADAYLTPHI KAYLASFVAG FDDDISKVKI SFMQSDGGLA PADSFCGFRA VLSGPAGGYI
GYAKTAHTPG GPPVIGFDMG GTSTDVSRYA GSVEQVFEAR LAGVTIQAPQ LDIKTVAAGG
GSRFFFREGR LAVGPQSVRA HPGPVCYRKG GQLATTDANL LLGRIRPEHF PRIFGPDEDQ
PLDAGAPSFS GTRAAFEAML SGEVHPFYEA TSPAGAPPRR MSVEQLAHGF LEVANEAAMC
RPIREMTQMR GHDAAAHVLA SFGGAGGQHA CAVARSLGMT RVYVHRHASI LSAVGIALAD
VVVEKQEAAA LTLGEPGAAE RVSVRHAALA AAVEEQLAAQ GFAPPLLRTD RFLNLRYAGT
DTAIMVSEPA AGGGAYAAAF EAQHRREFGF TFAERPVLID DIRVRGTGLS PPAPAAPTAA
ASGALPPPTS VGRTYFESGW EETPSYSLQS LAPGNVLEGP ALLLDDISTV VVEPNCTATV
TATGHLEILA APAEGAPSPS GDADPVQLSL YSHRFMGIAE QMGRTLQRTS VSTNIKERLD
FSCALFDASG GLVANAPHIP VHLGAMQDAV QLQQRRWEGD IHAGDVFLSN CPHTAGGSHL
PDLTVITPAF LPGDGDAPAF WVASRGHHAD IGGATPGSMP PFSHSLSEEG ARIVGFRLVS
RGVLQEEGVR SILAKSRNLT DNLSDLKAQV AANEMGLRLL ASLAAESSLA AVRSYMHHIQ
ANAEATVRAM LRAFAARAGL GANGVCTAAD QLDDGSEIRL AVTIDAAAGS ATFDFSGTSP
QSYSNLNAPR AVTYSAVIYS LRALCDTDMP LNQGCLAPVT FVLPEGCLLN PGETAAVVGG
NVLTSQRVVD VVLKAFGACA ASQGCMNNLT FGDETYGYYE TIAGGAGAGP DWDGRSGVHT
HMTNTRITDP EVLERRYPVV LRTFSLRAHS GGGGAHRGGD GVVREIEFLR PTDVSILSER
RAVPPYGLAG GEPGVRGQNL LLPAGGGAGP TVSLGGKAFV RVEAGARLRV LSPGGGGYGA
PAEAYSGGSR AK
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