ID R1EFB8_EMIHU Unreviewed; 1005 AA.
AC R1EFB8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0000259|PROSITE:PS51387};
GN ORFNames=EMIHUDRAFT_207722 {ECO:0000313|EMBL:EOD21696.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD21696.1};
RN [1] {ECO:0000313|EMBL:EOD21696.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD21696.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD21696}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the oxygen-dependent FAD-linked oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00005466}.
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DR EMBL; KB865837; EOD21696.1; -; Genomic_DNA.
DR RefSeq; XP_005774125.1; XM_005774068.1.
DR PaxDb; 2903-EOD21696; -.
DR EnsemblProtists; EOD21696; EOD21696; EMIHUDRAFT_207722.
DR GeneID; 17267203; -.
DR KEGG; ehx:EMIHUDRAFT_207722; -.
DR eggNOG; ENOG502QTE5; Eukaryota.
DR HOGENOM; CLU_298864_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.40.462.20; -; 1.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR42973; BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED; 1.
DR PANTHER; PTHR42973:SF39; FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 399..588
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT REGION 237..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1005 AA; 108353 MW; ABE06C185C340154 CRC64;
MQHKQHMHMH MHISHFAVPC DDSSSCSFPL QRFLQKTQCR TLLVANTKNA EILILFLNSI
NNMNMSENKT EVKARIMPAE DGSIKVVFFS APTSPPLLGA KAASGAKNAP VEDVTVAESG
AEAPLDESIL KQDPAAEEAT AAETVDSDRA KATFAAHKPR ANAVFWSKFV RPTDPPPART
EDAPALKPVT EDAPALEPGD ADWNVSTKEF PVEEPAPAGI DEWKTPSPLR KIERKGESNL
IDRSKKTTKN PTPIGRVDPN GFAALLGTDV DEEDLADGGA GEKTEPTSTR SGFRFGKFCS
TKLLCVFLTV AVGLGCSAFA LSSYRSGGVS SELLESVFVP DAAAIPDEDA ALACREAGLQ
VYASNSSLYG QLRMSFSKMY QAWPLVVCEA LAPEEDASLT VRELLKFRPP TQDQMQQATG
KIQHFVAISR QRNLSFAIRS GGHSNAGLSS TVGLSTLDVR GMSIVEPKFD SMTVTVGAGA
TAGQAQFSTV NITTNSDTFG AALPVGQKPS VGMTGLTLGG GFGFLTRYAG LLCDRLVSLD
AVLPSTGEIV HATADIHNEY HDLFWASCGG GGGNFAVVTE FEFNMVPVCG VTSDSDIPAG
ALQGPLEQYP CDVVMLHLFV PLDRPGLLSW YQEWSMRMDP RITPNFEVQN KTHGLIAGIF
IGSKEMFRRA LRLANPTDRH FIPVTVQELF DAATVKTFAQ ATTDLTGWTP NASTDVLVQS
FLDERSYFKY KSLFLVQPLS EDGQAILRDY AVVCGEEEEC GTGTNFTVVF EFQAMGGDPS
AQLPGGNAAG LFDDGSTFTY TFAPNNFSRI PVESTAFPQR NALHCLMLKA NSATEEGGDV
AFAHMENVYN MLLQTEQVQN GIRTEGREGQ PVVSYVNHID ANLPEAEFAQ FYAGVNSLKS
ASAFWTPSPS LAELSTDFWI NKLKQVRCKY NPDGLLYVNP LLAGLAGGPC TNDVVSQCSV
RTDGEECAIG GLGTCSCPVA GRQMLFSTRP VDQCECVPRH SEPFP
//
