ID R1EKP7_BOTPV Unreviewed; 527 AA.
AC R1EKP7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Putative vhs domain-containing protein {ECO:0000313|EMBL:EOD48112.1};
GN ORFNames=UCRNP2_5088 {ECO:0000313|EMBL:EOD48112.1};
OS Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus)
OS (Neofusicoccum parvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Neofusicoccum.
OX NCBI_TaxID=1287680 {ECO:0000313|EMBL:EOD48112.1, ECO:0000313|Proteomes:UP000013521};
RN [1] {ECO:0000313|Proteomes:UP000013521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-NP2 {ECO:0000313|Proteomes:UP000013521};
RX PubMed=23766404; DOI=10.1128/genomea.00339-13;
RA Blanco-Ulate B., Rolshausen P., Cantu D.;
RT "Draft genome sequence of Neofusicoccum parvum isolate UCR-NP2, a fungal
RT vascular pathogen associated with grapevine cankers.";
RL Genome Announc. 1:E0033913-E0033913(2013).
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
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DR EMBL; KB916240; EOD48112.1; -; Genomic_DNA.
DR RefSeq; XP_007584365.1; XM_007584303.1.
DR AlphaFoldDB; R1EKP7; -.
DR STRING; 1287680.R1EKP7; -.
DR KEGG; npa:UCRNP2_5088; -.
DR eggNOG; KOG1087; Eukaryota.
DR HOGENOM; CLU_017092_0_0_1; -.
DR OMA; KYIRDMH; -.
DR OrthoDB; 460229at2759; -.
DR Proteomes; UP000013521; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000013521};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 25..161
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 188..315
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 407..525
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 342..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 527 AA; 58104 MW; AB2C10704272C178 CRC64;
MAARDRFGGF AEPAMSPLQR YIMNACDPQN FEPNLALNIE IAELVNQKKG SAPREAAMEI
VKFVNSRNPN VSLLALNLLD ICVKNCGYPF HLQISTKEFL NELVRRFPER PPVHSSRVQN
RILELIEEWR STICMTSRYK EDLGFIRDMH RLLSYKGYTF PEIRREDAAV LNPSDNLRSP
EEMEQEEREA QSAKLQELIR RGTPHDLQEA NRLMKVMAGF DTRNKTDYRA KAAEEVGKIQ
QKAKLLEDML QKHQAGDQIK EGDVFEELAN ALASAHPKIQ KMCEEESDDH EAVAKLLEIN
DSIHRTLERY KLIKKGDVEG AAKIPKGTLG VSGAGVKKGP DNELSLIDFG GPEEAPAPTG
QAGASSSAPV PKGNALEDDL LGLNLGDDTF GQGGGISLGA TNGAALQPQP SSQTPVQNLL
GIRTDFTVSR QSDNTIHIQS VISNNTPAPI SELTMQFAVT KGYTLKLQPQ SGRLLQPNQQ
SGIAQNIDLQ GVEPGKGSSV KMRWRASYML GPERKEEQGE ITSLGVS
//
