ID R1EL65_EMIHU Unreviewed; 404 AA.
AC R1EL65;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:EOD21614.1};
GN ORFNames=EMIHUDRAFT_424653 {ECO:0000313|EMBL:EOD21614.1},
GN EMIHUDRAFT_438849 {ECO:0000313|EMBL:EOD05954.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD21614.1};
RN [1] {ECO:0000313|EMBL:EOD21614.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD21614.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD05954}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00038048}.
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DR EMBL; KB869934; EOD05954.1; -; Genomic_DNA.
DR EMBL; KB865838; EOD21614.1; -; Genomic_DNA.
DR RefSeq; XP_005758383.1; XM_005758326.1.
DR RefSeq; XP_005774043.1; XM_005773986.1.
DR PaxDb; 2903-EOD05954; -.
DR EnsemblProtists; EOD05954; EOD05954; EMIHUDRAFT_438849.
DR EnsemblProtists; EOD21614; EOD21614; EMIHUDRAFT_424653.
DR GeneID; 17252103; -.
DR GeneID; 17267159; -.
DR KEGG; ehx:EMIHUDRAFT_424653; -.
DR KEGG; ehx:EMIHUDRAFT_438849; -.
DR eggNOG; KOG2733; Eukaryota.
DR HOGENOM; CLU_031002_0_2_1; -.
DR OMA; YVARMEQ; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 7..135
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
SQ SEQUENCE 404 AA; 43247 MW; E0DE0ACBD694890B CRC64;
MGTEYDILLC GVTGFAGKLA AEHLLVKSYP IKWACCARNE AKAAAAVKTI ADRVGATALP
PIEVACLISD EAKLRAVVKK TKVVLTCAGP FEKYSQTLVK VCAEEGVHYA DITGESDFFR
KMIAEHDATA QKTGAKIVIH CGNDAIPWDL TVFEMSKLAR SKGAELAEAW TYGEFGATAA
ASGGTLTTAI YQLGKRRGGA KPDFDPLLKR PDGSKSESLT KITNPKQDVY CDEFAQYGGP
WIMGPVMANC VRRSNALLGY SASLTYADVM LRGHPTWAQW AGAKANEALV GAAVMAPRVF
ARFLPAPGEG PSREDMDAGY LKLHGRGRMV ERDGKETPLK STYHFPLDTG YLMTAQMLVE
AGMVLLEKAK AGPGGVLTPA AALGSDIVAR LDKELDAKFE MSEA
//
