ID R1ENY3_EMIHU Unreviewed; 751 AA.
AC R1ENY3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Minichromosome loss protein Mcl1 middle region domain-containing protein {ECO:0000259|Pfam:PF12341};
GN ORFNames=EMIHUDRAFT_450583 {ECO:0000313|EMBL:EOD24691.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD24691.1};
RN [1] {ECO:0000313|EMBL:EOD24691.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD24691.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD24691}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB865427; EOD24691.1; -; Genomic_DNA.
DR RefSeq; XP_005777120.1; XM_005777063.1.
DR STRING; 2903.R1ENY3; -.
DR PaxDb; 2903-EOD24691; -.
DR EnsemblProtists; EOD24691; EOD24691; EMIHUDRAFT_450583.
DR GeneID; 17270238; -.
DR KEGG; ehx:EMIHUDRAFT_450583; -.
DR eggNOG; KOG1274; Eukaryota.
DR HOGENOM; CLU_004219_3_0_1; -.
DR OMA; DIWHESK; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR022100; Mcl1_mid.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19932; WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; 1.
DR PANTHER; PTHR19932:SF10; WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1; 1.
DR Pfam; PF12341; Mcl1_mid; 2.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 141..182
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 380..568
FT /note="Minichromosome loss protein Mcl1 middle region"
FT /evidence="ECO:0000259|Pfam:PF12341"
FT DOMAIN 570..611
FT /note="Minichromosome loss protein Mcl1 middle region"
FT /evidence="ECO:0000259|Pfam:PF12341"
FT REGION 295..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 79306 MW; 16CB5A0FE4DEDC94 CRC64;
MPLDKGVHLK CAHTEGRGAI SYAPDGRHIV TCGEDTFVKI FEAEELSAEP RTLEIHDAPV
TALAMDRKGA RVVTGTDAHI ASVFSYPSGE GMRMLTRMQS AVRCIALDPK GRIAAVGAED
GAIRMCMVNA SGAGASQFVS VKGHTDSVLC LAFDPKGEYL ASSSADGTVR IWDIRDDPTT
VKTLSVCGRV LPGSAQQLGV CWHPQGETLA VPKGAGAILL DRGTWEETAT FESGGAGKDG
HSRDIFVWDA ACGESLDRHR GDATPCGLCW SPTANTLCFL DDSGQLGIWS QPVPAHYPPP
GSTPAAAAGG EEGGDESKGG RRRLRKVVHD SDDGGFSDHD DDEAVEAAML AAQLKMHGTH
GPQPPAASEP RRSACPPRQN LTGMVLSRDE NTYSAIEVEF NDATKHRTMR LTDHYGFSMA
ALDEAAVLFA SRSNHGKTRN PSTVVYRPLA SWAPNSDWQV QLEKGEEAVA VAVGHKFALV
ATSARYLRVY SHTGAPRSLL CHGGPLVALA ASRGLAALAL LVTLYDLREP ARPVRLASEL
LPLSPGATLD WVGFSEAGAL STVDSAGVAE HHWVVGLTGA QLMCILCKGD DKYPATLPRP
VLTALPLAMP LACSEPAEPQ LEAQRIAAMV ELDEYRLAAT EAGLGEEETA EHTMRLVTKI
DSLALKLFQT ANGTERNAAE RARGALKLAN HFKLGPLADR LSRLLEAPAT PAPRGVEPTA
TGKSVLELGG TGKAPKRKAG AAGAGGAKKA R
//
