ID R1EXR1_EMIHU Unreviewed; 596 AA.
AC R1EXR1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Kringle domain-containing protein {ECO:0000259|PROSITE:PS50070};
GN ORFNames=EMIHUDRAFT_231980 {ECO:0000313|EMBL:EOD31385.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD31385.1};
RN [1] {ECO:0000313|EMBL:EOD31385.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD31385.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD31385}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB864624; EOD31385.1; -; Genomic_DNA.
DR RefSeq; XP_005783814.1; XM_005783757.1.
DR STRING; 2903.R1EXR1; -.
DR PaxDb; 2903-EOD31385; -.
DR EnsemblProtists; EOD31385; EOD31385; EMIHUDRAFT_231980.
DR GeneID; 17276658; -.
DR KEGG; ehx:EMIHUDRAFT_231980; -.
DR eggNOG; ENOG502QVNP; Eukaryota.
DR HOGENOM; CLU_435084_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR CDD; cd00108; KR; 2.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 3.30.300.320; -; 1.
DR Gene3D; 2.40.20.10; Plasminogen Kringle 4; 2.
DR InterPro; IPR000001; Kringle.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR018056; Kringle_CS.
DR InterPro; IPR038178; Kringle_sf.
DR InterPro; IPR000800; Notch_dom.
DR PANTHER; PTHR24261:SF7; KRINGLE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24261; PLASMINOGEN-RELATED; 1.
DR Pfam; PF00051; Kringle; 2.
DR Pfam; PF00066; Notch; 3.
DR PRINTS; PR00018; KRINGLE.
DR SMART; SM00130; KR; 2.
DR SMART; SM00004; NL; 2.
DR SUPFAM; SSF57440; Kringle-like; 2.
DR PROSITE; PS00021; KRINGLE_1; 1.
DR PROSITE; PS50070; KRINGLE_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kringle {ECO:0000256|ARBA:ARBA00022572};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..596
FT /note="Kringle domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014592567"
FT DOMAIN 81..165
FT /note="Kringle"
FT /evidence="ECO:0000259|PROSITE:PS50070"
FT DOMAIN 472..545
FT /note="Kringle"
FT /evidence="ECO:0000259|PROSITE:PS50070"
FT REGION 167..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 596 AA; 65826 MW; 36C4BDFDE0D21845 CRC64;
MRRIVLLAVS YSVARGSEVD DVTFEPAYGY WDDDSYGYMI DDGFCAWQCD PEYVSDGECD
EMCNVPECEF DGVDCFHGYG ECYTQADGSD YRGAVNVTEG GLSCQAWSQQ WPQRHDRIHT
NYPHGGLGGH NSCRNPDGET GPWCYTTDPN VRWQHCTIPL PQGTCAGHHA ANRTAPPPRP
ASDAGSGEQS SSDMYDDYNM DYPYPPWELS YDIFPVVFAP EVSSPIELNT MISGSVEEHT
YVFYEVEIPQ SVQEVKVVVV PEEGDPDLYV SFDNPFPTGA NYTFLSDNYG VEEWTLGRYN
YLFCGAAGTE AACTMYLSIL AYDEHSTFSL VVYGVEEASA DDAPSTLCAP GCEWLSLGDG
TCNQQCDVEE CFFDRGDCAC DSAESADCTD GCPVSCKPEW IGDHYCDEAC FRASCQWDKH
DCLKKGETPC ADDCLPTSLG DGECDAACNV ESCNFDIDDC FHNNNECYER QDGADYRGKV
ATTESGYPCQ RWSDQSPQQH TRTAQHYPRS GLGGHNFCRN PDREERPWCY VADKDSGKRW
DYCAIGEPSN ARLKRKRAMK SGGFTQYGGH DDGVLGTGVE IKPVVPESAA APGASA
//
