ID R1F194_9GAMM Unreviewed; 2093 AA.
AC R1F194;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Nonribosomal peptide synthetase {ECO:0000313|EMBL:EOD53753.1};
GN ORFNames=G113_17911 {ECO:0000313|EMBL:EOD53753.1};
OS Aeromonas molluscorum 848.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=1268236 {ECO:0000313|EMBL:EOD53753.1, ECO:0000313|Proteomes:UP000013526};
RN [1] {ECO:0000313|EMBL:EOD53753.1, ECO:0000313|Proteomes:UP000013526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=848 {ECO:0000313|EMBL:EOD53753.1,
RC ECO:0000313|Proteomes:UP000013526};
RX PubMed=23788549;
RA Spataro N., Farfan M., Albarral V., Sanglas A., Loren J.G., Fuste M.C.,
RA Bosch E.;
RT "Draft Genome Sequence of Aeromonas molluscorum Strain 848TT, Isolated from
RT Bivalve Molluscs.";
RL Genome Announc. 1:E00382-13(2013).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOD53753.1}.
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DR EMBL; AQGQ01000173; EOD53753.1; -; Genomic_DNA.
DR RefSeq; WP_005907825.1; NZ_AQGQ01000173.1.
DR PATRIC; fig|1268236.3.peg.3486; -.
DR OrthoDB; 9757559at2; -.
DR Proteomes; UP000013526; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF18563; TubC_N; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1024..1097
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2093 AA; 229649 MW; 35EA0C6813AEBCF4 CRC64;
MNNMILLLKQ LERQGVKLAL NDKGQLISQS SKEAVTPAIG ATIKAHKDEL VRCLAARAAF
EAPILAQREA EGARQGPLSS SQSGLWFIEQ YEEASHLYNM PVYFRVKGEL DTAALEFAFD
HLFARHPSMR TRFIKDEAGR GAQEILPHVP FKLQIEDVSA EPIAEREAYV ARRVREEIGR
PFSLTQGDLS RVHLIRLGSR EHVLLITQHH IISDGWSVKN MFADLKRAFL AHQNRELLQV
SELPLTYIDY ARWFNSDRFL DYHAEFKPFW VDRLGGSPEV HGLPLDKPRP AHQDSGGELV
FSTIDNTLWE SFKRLCQRHS TSNFIGLHAL FALLMVRQSG EKEVVIGTPL AYRERHEIES
LVGFFVNTLV LRTQLSGKPS FVDYLQQCRE EDLAAFDHQL YRFEALAEAI GADRTTAINP
IFQIMLVYQA KVDFNDLIPG CQLVEETSPV LPAKTDISVK VTELMDSVRV DWLFATALFE
RETIQALADR LLHLMRAVVA APETDIWQLP LEAGTDQAAL AAALADLPPD YHNRDTLLCH
IERRAGKCPD ALAVSDGAQS LTYGELEVRA NRLAHWLLAK GVTPGAAIGI QARRDVAFVI
ALLACWKAGA AYVPLDPAYP AERLAHILGD ASISLVLGGV PDPRLGEALA GTIAEYHDLH
QLALDKMPTS TPALPRDAAM LAQIIYTSGS TGLPKGVMVE QGSLVNLMAD HGERIALGKG
GAMFNCMSLS FDAGNMTSLL PLYCGAALHF GEPGEGVIGA AIACAASHMI LPTALLANLL
PAADLGSLKA IGFGGEACPS SLVERWGERV ALFNMYGPTE CTVTALCARL TPGAPITIGR
PVNNLKALIL DEGGNLCPVG VPGELCLSGL GLARGYLNLP ERTQEAFIEL ALADRTHRLY
RTGDRALMRR DGNIQYLGRI DEQIKLRGYR IEPGEIETQI AALEPAIRQI KVVVQEGRLL
AYASLQAGAT EPDGEALLQR AGECLPEYMV PVRLCWLTEM PLTPNGKLDL RRLPAIDWQE
SKSEPQSELE QTVLAIWQGV LKQSLGVEDD FFRLGGDSIL SIQLTTRLRD AGLHCSVKDV
FEAKTVRRLC RQLGQQQAVS HQTEQGNLVG DFPLHPIQHW FFEQGFAKPG HWNQGVILRL
PAGIDDDTLA GWLTTLRQHH DALRLAVTPT GQRYLAELAL PPLPTLDAGT LGGAELQARL
TELQGELDPA SGHTLAWARL RNLSLAGDRG GDRETVEGLF LAFHHLVIDA VSWRILAEDL
ARVSRGEPLS AKGSSYRQWG EGLAAYAKRE EDQLGFWLAQ GEGSLGHLLE AARAVDGRAA
ASLLQLSQET TARLIDTANQ AYFTRVPDLL LAALTRTLSE QGYGSRHCVM LEGHGREAID
AELDVSRTLG WFTSTYPLAL ADAGVWDALV CATKEQLRAV PDKGVGFNAL RLHHPRGSEL
PQALVVFNYL GVSHQGEAAQ PWQPLPMAPG APTSPDNLPR ELVSLHGGVF DGRLTLRQVG
ALNQQGSDAL MARLADNLTA LVEHCCNLKA PRHTPSDFPG IALSQSSLDR VLSGREVETL
LPMTSLQQSM FHHRALLPRD HAYHLQTEID YQQPLDLAVY RQAWQGQIAR WPALRSELVL
ADGVALQRIL KCAELPFHYE DLSEVENAEA RVQAYREQDL ARPIPLKQAP LLRLACFKLA
PDHHKVIFSA HHSVLDGWSG PVLLGSLHRG YQALMNGLLP QREPDTAWLE FGRHIASQAR
SAEAYWQGRG ELLAKPNDLA CLFGVTLDAG SSGRHTQQRP AVCATALPTE VATLLAHRAR
DLGVTSGLLA QYTWHRLLAR RSGDAVTLVG NVTPGRDYPI EGITASVGLY INSLPLALEW
RTEVTLAEHI AQLQTDLMAL NEHGTQSLAA LTKGRSRLFQ SLFVFENYPM PAVPATPEPH
QLVPQFGTVV EKVELPLSLV VSSRGETLQL RLEFDGEQIP EAQAEEVLAD WRAELGWLAQ
ADLNQPAKPA AAASSPAMAQ GAATRAESDL AQPPAEARAL VALWERQCGV PGIWQQTLMD
LGIDSVQQLA LLAALNEALA QDRVPLTLQT LKAHPSPSRL YRHWLVRQEE AVS
//
