ID R1FVY0_BOTPV Unreviewed; 373 AA.
AC R1FVY0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=UCRNP2_10046 {ECO:0000313|EMBL:EOD43265.1};
OS Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus)
OS (Neofusicoccum parvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Neofusicoccum.
OX NCBI_TaxID=1287680 {ECO:0000313|EMBL:EOD43265.1, ECO:0000313|Proteomes:UP000013521};
RN [1] {ECO:0000313|Proteomes:UP000013521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-NP2 {ECO:0000313|Proteomes:UP000013521};
RX PubMed=23766404; DOI=10.1128/genomea.00339-13;
RA Blanco-Ulate B., Rolshausen P., Cantu D.;
RT "Draft genome sequence of Neofusicoccum parvum isolate UCR-NP2, a fungal
RT vascular pathogen associated with grapevine cankers.";
RL Genome Announc. 1:E0033913-E0033913(2013).
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|RuleBase:RU362007}.
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DR EMBL; KB916880; EOD43265.1; -; Genomic_DNA.
DR RefSeq; XP_007589277.1; XM_007589215.1.
DR AlphaFoldDB; R1FVY0; -.
DR STRING; 1287680.R1FVY0; -.
DR KEGG; npa:UCRNP2_10046; -.
DR eggNOG; KOG1369; Eukaryota.
DR HOGENOM; CLU_014393_4_0_1; -.
DR OMA; HYPHYKE; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000013521; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF29; PHOSPHOTRANSFERASE; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000313|EMBL:EOD43265.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000013521};
KW Transferase {ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 87..367
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 373 AA; 38639 MW; 15537E5863904532 CRC64;
MGKGFGIVSD LNLGEMLLAG YARHCTDMTP ATNGHPPPEK ATATAAAAAP TAAAATRLPR
LRIAAITNDT VATYASLAYS SNSRVAMGLV VGTGTNATVP MPVASLAAFK TAPLDLLPRG
PGGSSPDIVV VNTEWSVVGT DEPLRALGVP TPWDAALSAA CESPGFQPVE YMTAGRYLGE
LVRLVLVQLL LPPEEGGREE ELPPRLLEKN AVSTRFLATA VALAGDDDAL KRSLDELYPP
PPSSAAGRAF AWTAQRVGLL RAVAEAVQVR SAALVAAMIV GLLARVGEVQ LDGEAGGDDG
AAEEVEKEEL VVAHTGGVIL QYPGYLEICE KWIDTLISKG SRRNAGKRVV LSEAKDGGVI
GAAVLAGMFA DVR
//
