ID   R1FWT2_9PSEU            Unreviewed;       298 AA.
AC   R1FWT2;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=EamA domain-containing protein {ECO:0000259|Pfam:PF00892};
GN   ORFNames=H480_35121 {ECO:0000313|EMBL:EOD63812.1};
OS   Amycolatopsis vancoresmycina DSM 44592.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD63812.1, ECO:0000313|Proteomes:UP000014139};
RN   [1] {ECO:0000313|EMBL:EOD63812.1, ECO:0000313|Proteomes:UP000014139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD63812.1,
RC   ECO:0000313|Proteomes:UP000014139};
RA   Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT   "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOD63812.1}.
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DR   EMBL; AOUO01000588; EOD63812.1; -; Genomic_DNA.
DR   AlphaFoldDB; R1FWT2; -.
DR   eggNOG; COG0697; Bacteria.
DR   Proteomes; UP000014139; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000620; EamA_dom.
DR   PANTHER; PTHR32322:SF9; AMINO-ACID METABOLITE EFFLUX PUMP-RELATED; 1.
DR   PANTHER; PTHR32322; INNER MEMBRANE TRANSPORTER; 1.
DR   Pfam; PF00892; EamA; 2.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        30..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        261..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..132
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
FT   DOMAIN          143..276
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
SQ   SEQUENCE   298 AA;  30671 MW;  466ECA51388052E5 CRC64;
     MRIAVLALLW GSGFLWIKLA LTGLSPVHLT LVRCALGALT LLALAFAARQ RLPRDRGTWA
     RLVVAAFFCN ALPFALFGIG ERTVDSGVAG VMNATTPLWS LLIGVTLGTE RRLTPVRLLG
     LILGFAGIVV IFAPWRQSGL LSAGALALLG AGLSYAIAFA YMARKLPPDG APLALSAAQL
     MTATALTALA LPVASAAPHL TLTAVVAVTI LGVFGTGITF HLNYRLIADE GPTAAATVGY
     LLPVVSVGLG ALFLGEPLTP RVVGGMVVVL VAVGLTRWRP QVPANCPASS AGGLATPK
//