ID R1FXD3_EMIHU Unreviewed; 1775 AA.
AC R1FXD3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=FHA domain-containing protein {ECO:0000259|PROSITE:PS50006};
GN ORFNames=EMIHUDRAFT_98050 {ECO:0000313|EMBL:EOD38174.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD38174.1};
RN [1] {ECO:0000313|EMBL:EOD38174.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD38174.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD38174}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB864046; EOD38174.1; -; Genomic_DNA.
DR RefSeq; XP_005790603.1; XM_005790546.1.
DR PaxDb; 2903-EOD38174; -.
DR EnsemblProtists; EOD38174; EOD38174; EMIHUDRAFT_98050.
DR GeneID; 17283444; -.
DR KEGG; ehx:EMIHUDRAFT_98050; -.
DR eggNOG; ENOG502QU12; Eukaryota.
DR HOGENOM; CLU_238732_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR36681:SF3; DYNAMIN N-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR36681; NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF00498; FHA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 28..75
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 131..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1716..1775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..189
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..263
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1744..1758
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1775 AA; 183618 MW; D86965300462F2D9 CRC64;
MELALVSTVN GARAGRPSRI ALAPGAKLTV GRDDSQTISL SAGHISRRHA VIHVSEDGRS
VRIEDVSRKN GCRVQHGASA TLLLSTAEAA ASAVVGEGGV VTFGQPASQP RSAANDLRYV
LRAVADPAAS TASASAAASS VEAGEEEASL GEEDEMEVEP PGDRAGHDSF IFEDSQPPPP
PPPEPPSAPA AQAGAVEPHP AAGVSAVEPH PQSNIGAVEP HPAAAPAVQP QTGEGGSDVK
SPKMQPPPPP RPSQPPPAAP PPAPFLLAAL SGLPGVLYRP AAEAELCSPR VLLLSRHIAA
AVRGDEELAR LYGSALDAGA AAAPPPAPQP APDAAAFAAA LPALPPAGGS DDEEGGEADV
RRRLLRVVAS LKPSGTLAHA ASVDFVPPLL RAEGMAEPVA FPLPEAHAQA LRSLGEPASD
GCGVWVRAER LELGAIKEWE ESLRPAVRKA LRALGVDKTT ESSASERLAR LATVWEASRR
GGSSEGSSTA QPSSGSGVAP PSKLVYFLPR DAAGAAATSL ASLKGDGAAL SAALHEAGFD
VLLATLTRAV TRLNSHGPPF KIDLSVVWHE ADYWEGEKPD ATEGGGMVWP QTEPFVERFS
REALVLWPRA SRLGVLPPEF AISRLRAALD EVEAGRAPSE ASLAGSKDVS SLLKVCTARL
DPSLELLELA ARPGVSACDC SRVVETAAKC LAVSPCGLGA LHVSRHLADA IRLHGWPALK
ASIRACFCEA MAESGLEALH ASGWELLLML RDEVEEEGSD SHCVNLAVEL EPRLRLPAAS
VQSRGGGENA LARTLRASVR TLAPIEVAAA EGGLQHRRGI ATRAILHNEQ RFPAASLPFL
RALVSLRTDL PPDSEAWNSL ADSSVRQLCA RLAEGAAEGA DAPILSVASP RFVETAGLLL
VMGLAERCLP SLQSSLPCSA PLLRAITVLL ADEAHAAAVA CSGEWLALLL GAIRHPVTEA
PATELQEALV LGYVAAGRFG THGLSTCRDR VAAAIVENVS GAWSTEVMTA RPPRPPRPVA
FAKSAADATQ VLVSSVLKLH EAIDETDRQQ SAFRKLLSAA LDAKRSTLRA RPPPLKDWSV
NARLVCDRGD ERRSAFAGSV GAPPEPLRSV CRDCHRVQRF LDQRSGDVQR EVFGGPAFTH
GGHTSLAVAA AAKGLEGLLS VKASAAELRE EEASRALYDE HGKARALRRQ RPPPADLLKY
ERLLRALLSA QQGGKEAAEE LSAALEAAGG ERDPLTPREA AAEAAASVSS SASAPAAGAP
ALSGEALVRW VASHFPAAAR AAAEVSELEI ATSMSLAELR AVLLPDNLPR APPGEVQLRL
RAVQTRLRLL AGGGGAVAAP EPESFALLAP PPADAPPFHV IVAGDTGAGK STLLNALLGY
EILPTSCCAA CTATVIDASW GEVWSATVEF VAEEVSPPSA EAWRETVTAA EAHARAGGDS
SAAAEASWER ATAVYGSPLA DATTLLARLD VAELLGTSRQ LSAGGDADLA DLVAPFVDAS
ASASDDSGDL SPRHLWPLVA RVHLRGPFAV TAGGVLLRDV PGLADESASR SGVLERVLEA
ADSLLLVSSI NRAANDKGAK SLLPLPLRRE LLDSGYLGDL AFIASKARLR TPSDMMSMSP
RHDADLLTPS EVFPVSSRDA LVLEGVRPGD GEARVFSSAA ETRIPALRAY IALSAAAHHA
RAAAGAPPRR RVGAVLLRCL RAAAPSAAAP SAAAPSAASA AGSSPSAVEP AVAQPGLRSS
PSTNRHRTRV DSPGDGPPGK RPRAEPAVVD LCDSD
//
