ID R1GUU0_BOTPV Unreviewed; 317 AA.
AC R1GUU0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Putative rna methylase protein {ECO:0000313|EMBL:EOD52086.1};
GN ORFNames=UCRNP2_1184 {ECO:0000313|EMBL:EOD52086.1};
OS Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus)
OS (Neofusicoccum parvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Neofusicoccum.
OX NCBI_TaxID=1287680 {ECO:0000313|EMBL:EOD52086.1, ECO:0000313|Proteomes:UP000013521};
RN [1] {ECO:0000313|Proteomes:UP000013521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-NP2 {ECO:0000313|Proteomes:UP000013521};
RX PubMed=23766404; DOI=10.1128/genomea.00339-13;
RA Blanco-Ulate B., Rolshausen P., Cantu D.;
RT "Draft genome sequence of Neofusicoccum parvum isolate UCR-NP2, a fungal
RT vascular pathogen associated with grapevine cankers.";
RL Genome Announc. 1:E0033913-E0033913(2013).
CC -!- FUNCTION: Catalytic subunit of an S-adenosyl-L-methionine-dependent
CC tRNA methyltransferase complex that mediates the methylation of the
CC guanosine nucleotide at position 10 (m2G10) in tRNAs.
CC {ECO:0000256|ARBA:ARBA00002425}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB915786; EOD52086.1; -; Genomic_DNA.
DR RefSeq; XP_007580505.1; XM_007580443.1.
DR AlphaFoldDB; R1GUU0; -.
DR STRING; 1287680.R1GUU0; -.
DR KEGG; npa:UCRNP2_1184; -.
DR eggNOG; KOG2671; Eukaryota.
DR HOGENOM; CLU_029646_1_0_1; -.
DR OMA; VMGTEIN; -.
DR OrthoDB; 5488599at2759; -.
DR Proteomes; UP000013521; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016691; tRNA_mtfrase_TRM11.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51627; SAM_MT_TRM11; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EOD52086.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013521};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 178..293
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
SQ SEQUENCE 317 AA; 34641 MW; 4AA726855B470571 CRC64;
MPEYLIRCVQ VHESFRRAEL ESLATLAGVD LEFVSYSENT PFALVNLPSD AAARAIISRS
ILSAGIYELW GSGTDEASLH ASVTSRTSAR WPSYATTPFR FSVDTFQGKR SSASQRALID
SFRYMNFAGP IRLRDAAALH LCVFEEYAQF ADQPSRCFLG RWVADGARRA VVTYDLKKRR
YISTTSMDAE LALVTANMAL AAPGKLFFDP FVGTGSFTVA AAHFGAQAVG ADIDGRSIRG
KADGRDVVAN FGQYGLMGRF LDNIVSDLTN SPLRRGRWLD GIVCDPPYGV REGLKVLGRK
DGGGQEAVMI DGEWAHL
//
