ID   R1HHP7_9PSEU            Unreviewed;       341 AA.
AC   R1HHP7;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=N-acylneuraminate-9-phosphate synthase {ECO:0000313|EMBL:EOD63120.1};
GN   ORFNames=H480_38675 {ECO:0000313|EMBL:EOD63120.1};
OS   Amycolatopsis vancoresmycina DSM 44592.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD63120.1, ECO:0000313|Proteomes:UP000014139};
RN   [1] {ECO:0000313|EMBL:EOD63120.1, ECO:0000313|Proteomes:UP000014139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD63120.1,
RC   ECO:0000313|Proteomes:UP000014139};
RA   Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT   "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOD63120.1}.
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DR   EMBL; AOUO01000657; EOD63120.1; -; Genomic_DNA.
DR   RefSeq; WP_004560758.1; NZ_AOUO01000657.1.
DR   AlphaFoldDB; R1HHP7; -.
DR   PATRIC; fig|1292037.4.peg.7260; -.
DR   eggNOG; COG2089; Bacteria.
DR   OrthoDB; 9814210at2; -.
DR   Proteomes; UP000014139; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
FT   DOMAIN          284..341
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   341 AA;  36477 MW;  2B4AF6D142D5F203 CRC64;
     MFMLGEHPVG ADHPPLVIAE IGINHEGDPK KAHKMVDDAA DAGVQVVKIQ THVVDDEMIP
     NDVVPGNADE PIWDMMNRVA LTAEDEREIK AHAEERGLVF LSTPFSRAAA DRLADLGVEG
     FKIGSGECNN YPLIRHVASF GKPVILSTGM NDIASITPAV EILRAAGVGF ALLHCTSLYP
     TPPEQVRLGA LAELHAAFPD AELGLSDHTV TIYPCLGAVA LGASVLERHF TSDMSWPGPD
     IPVSSTPAEF KQLVEGSRLI HAARGGSKQI LAEEQPTIDF AYACVVTTKD VAEGETLTTD
     NIWVKRPGTG EIKAKDYESL LGRAVTRALP ANTQVSWADL G
//