ID   R1I1G1_9PSEU            Unreviewed;       519 AA.
AC   R1I1G1;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=AMP-dependent synthetase/ligase {ECO:0000313|EMBL:EOD66361.1};
GN   ORFNames=H480_22097 {ECO:0000313|EMBL:EOD66361.1};
OS   Amycolatopsis vancoresmycina DSM 44592.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD66361.1, ECO:0000313|Proteomes:UP000014139};
RN   [1] {ECO:0000313|EMBL:EOD66361.1, ECO:0000313|Proteomes:UP000014139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD66361.1,
RC   ECO:0000313|Proteomes:UP000014139};
RA   Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT   "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOD66361.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOUO01000318; EOD66361.1; -; Genomic_DNA.
DR   RefSeq; WP_003091361.1; NZ_AOUO01000318.1.
DR   AlphaFoldDB; R1I1G1; -.
DR   PATRIC; fig|1292037.4.peg.4191; -.
DR   eggNOG; COG0318; Bacteria.
DR   OrthoDB; 4507402at2; -.
DR   Proteomes; UP000014139; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd04433; AFD_class_I; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EOD66361.1}.
FT   DOMAIN          40..371
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          425..503
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
FT   REGION          278..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   519 AA;  55207 MW;  1865CFC487A3992D CRC64;
     MSAVWTSTAG VAIPDLVPGE LRRAWVRQGR CPGTDIYRSF TEHVDAHPDR QAVLDDAGPV
     TYAELDHAVS ATAAGLLAAG LGRRDVIGIR MVNSRHAVAA ELAVAAVGAV SMPFPAGRGR
     RDALSLLRRA KATGLLVDRG TEGLRALPSL RVTLAPEEFA TSAAAARPTP EVASGDPARI
     LVSSGSETEP KMVAYSHDAF LGGRANYVRA LHEDDTPMRN LVLVPLSSSF GSCGVPVTVA
     ALGATLIVQR QFDPDATLRT IGEHRPTHVF GVPTMLSRLA GRHPPRRPRG LRALVSSGAP
     MPPSTERRIR AGFRTPVILV YGSTDGVNCH NARDGRPDPA VARITIADGS GRPLPRGATG
     EIHALGPMTP LSYVADHELN ARYRTPGGWV RTGDHGFLDE QGVLHVTGRA RQVVLRGGRS
     ISPAEVELCL SGHPALAEVS CVGIPDPDLG ELLCACIVPH ADHPEPDLAE LTDYLRIHHE
     FEPVKLPERL IVLPSLPLGP TGKVCRATLV QLAACDWRF
//