ID R2RX18_9ENTE Unreviewed; 702 AA.
AC R2RX18;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN ORFNames=UAS_02002 {ECO:0000313|EMBL:EOH85101.1};
OS Enterococcus asini ATCC 700915.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158606 {ECO:0000313|EMBL:EOH85101.1, ECO:0000313|Proteomes:UP000013777};
RN [1] {ECO:0000313|EMBL:EOH85101.1, ECO:0000313|Proteomes:UP000013777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700915 {ECO:0000313|EMBL:EOH85101.1,
RC ECO:0000313|Proteomes:UP000013777};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus asini ATCC_700915.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH85101.1}.
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DR EMBL; AJAP01000022; EOH85101.1; -; Genomic_DNA.
DR RefSeq; WP_010754624.1; NZ_KB946294.1.
DR AlphaFoldDB; R2RX18; -.
DR STRING; 57732.RU94_GL002157; -.
DR GeneID; 78364786; -.
DR PATRIC; fig|1158606.3.peg.1949; -.
DR eggNOG; COG3973; Bacteria.
DR HOGENOM; CLU_010312_4_0_9; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000013777; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000013777}.
FT DOMAIN 203..561
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT COILED 61..88
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 224..231
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 702 AA; 79787 MW; 9052BD7E02EF5505 CRC64;
MENEAQHLQM VYQQLLAAKG ELSQLIQEKS QSGRASLQEM AGEVRVNFDS YLDNLDTFSA
IESLNRQIDQ YNLQLASATE TLAQVQRLLP APYFGKITVD FLDGQAPEAF YIGINGFTRD
NEALIHDWRS PIAELFYNNE LGSSSYQVRG QVIPVETKQR RQLLTDHDRL LNYFDTGTTI
QDEVLLAALA EDRSREMQDI TATIQTEQNQ IIRDHDAQVL LVNGVAGSGK TSTVLQRIAY
LLYQNRERYT PEDMLILSPN QRFAHYIAGV LPALGEANPP TLTLLELLQT LGHVEESEEE
YFLRISQEAV SEETAVLRSV ALMEYLERDL DFAPQFLPIT KKGKTILSKE YLQQIFAQTP
AGPFAQRIQG MKQRLVQEWE RRLIKDSRKE RVQQQLLDLT EAQQEKLLGK VLSETDEEQL
ASFALTLLRR KYAFVSKALA TYAWLDEAAM FAQVYQEYQG VPLQAGTMTV DLAVARGYFH
QVQIEPLKHR DYQVILVDEV QDYSPAALYL LKALYPKSRF TLVGDDNQAI FNSHTLFGTM
QELFKEKQPR YYALTKSYRT TGNITAFFAS LVADKMTMEI LPVRPAGSPV VYREFQDPAS
FAKILQDFQK VIGPAEQLTV ITKTQAEAEK LQHFASSQVS VYPVALAKGL EFPHVLLYDV
SEENYHSERG VRLLYTAASR STKELWITYQ GTPAAVLPLH QQ
//
