ID R2SDS4_9ENTE Unreviewed; 385 AA.
AC R2SDS4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Tyr recombinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=UAU_03540 {ECO:0000313|EMBL:EOH91001.1};
OS Enterococcus pallens ATCC BAA-351.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158607 {ECO:0000313|EMBL:EOH91001.1, ECO:0000313|Proteomes:UP000013782};
RN [1] {ECO:0000313|EMBL:EOH91001.1, ECO:0000313|Proteomes:UP000013782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-351 {ECO:0000313|EMBL:EOH91001.1,
RC ECO:0000313|Proteomes:UP000013782};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus pallens BAA-351.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH91001.1}.
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DR EMBL; AJAQ01000035; EOH91001.1; -; Genomic_DNA.
DR AlphaFoldDB; R2SDS4; -.
DR STRING; 160454.RV10_GL004516; -.
DR PATRIC; fig|1158607.3.peg.3536; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_17_1_9; -.
DR Proteomes; UP000013782; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF6; PROPHAGE INTEGRASE INTA-RELATED; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000013782};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 82..164
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 185..378
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 385 AA; 44429 MW; C2375879AA50C8D9 CRC64;
MVSRDRQKSR RSERMKEMRR GENIYRRKDN RWEGRYSKGK HADGRKKYGS VYGKSLQEVR
EKLYPLKLKY QIYQAIHGES AMTLNEWGYR WLYEVQSGIK QSTYANYEHK LVHYVLSVIG
NYGLNELDEE VGEELLNSLI DQALKPSTIQ VIFRITKQCM KEAIRKKLIK ENPFEGIQLP
KVVKNKNQAL TKQEQKRLEA TALKEENGKG LPTFIALHAG LRIGEISALK WTDIDFDNDM
IHVQSTYQRI LGVYNGKKTE LIYSSSKTAS SIRSIPLGRT LKRLLVQQKK QSKGEFVLCR
GNKPLEPRLL TAHFHRIREK AGLTQTHFHQ LRHTFATRCL ESQGDIVSVS ALMGHSSTQM
TLDTYASALV EQKIQVVAQM EKTIA
//
