ID   R2SRL0_9ENTE            Unreviewed;       731 AA.
AC   R2SRL0;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:EOH97900.1};
GN   ORFNames=UAU_00568 {ECO:0000313|EMBL:EOH97900.1};
OS   Enterococcus pallens ATCC BAA-351.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1158607 {ECO:0000313|EMBL:EOH97900.1, ECO:0000313|Proteomes:UP000013782};
RN   [1] {ECO:0000313|EMBL:EOH97900.1, ECO:0000313|Proteomes:UP000013782}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-351 {ECO:0000313|EMBL:EOH97900.1,
RC   ECO:0000313|Proteomes:UP000013782};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Enterococcus pallens BAA-351.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOH97900.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJAQ01000001; EOH97900.1; -; Genomic_DNA.
DR   RefSeq; WP_010755631.1; NZ_KB946300.1.
DR   AlphaFoldDB; R2SRL0; -.
DR   STRING; 160454.RV10_GL000864; -.
DR   PATRIC; fig|1158607.3.peg.573; -.
DR   eggNOG; COG1328; Bacteria.
DR   HOGENOM; CLU_002707_2_0_9; -.
DR   OrthoDB; 9804622at2; -.
DR   Proteomes; UP000013782; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01675; RNR_III; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW   ProRule:PRU00493}; Reference proteome {ECO:0000313|Proteomes:UP000013782}.
FT   DOMAIN          21..116
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
FT   DOMAIN          606..731
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000259|PROSITE:PS51149"
FT   MOD_RES         704
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ   SEQUENCE   731 AA;  83766 MW;  F50EFD74ED9117C6 CRC64;
     MMEIRTKDAQ VNDFQPTLKS MRVIKRDGRH VAFDDQKIYD ALIKAETKIH GTIDPLAHGR
     IQSIVERVDA ELAQRFTDNV KIYEIQNIVE HILLESNEYE LAEEYINYRT QRDFSRSKAT
     DINFTIGKLI NKDQSVVNEN ANKDSDVFNT QRDLTAGIVG KSIGLKMLPP HVANAHQKGD
     IHYHDLDYHP YTPMTNCCLI DFEGMLNNGF KIGNADVESP KSIQTATAQI SQIIANVASS
     QYGGCSADRV DELLAPFARL NYEKHMKDAE EWIENPERRE EFAKQKTRKD IYDAMQSLEY
     EINTLFTSNG QTPFTSLGFG LGTDWFEREI QKAILQIRID GLGIEKRTAI FPKLIFTLRR
     GVNLDAADPN YDVKQLALEC ATKRMYPDIL NYDRLVELTG SFKVPMGCRS FLQGWKDENG
     QEVNVGRMNL GVVTLNLPRI AMEAAGDRDK FWSLLEERLQ TAKDALVFRV DRCKEATPAN
     APILYQYGAF GKRLKRTDSV DELFKNKRAT VSLGYIGLYE VAASFFGGDW ESNPEAKEFT
     LDILKDLKQH TDAWGNEYGY HFSVYSTPSE SLTDRFCRLD LERFGIVENI TDKEYYTNSF
     HYDVRKNPTP FEKLDFEKDY PKYCSGGFIH YCEYPVLQQN PKALEAVWDY GYDRIGYLGT
     NTPIDHCYEC GFEGDFKPTK RGFECPQCGN HDPKSCDVVK RTCGYLGNPQ QRPMVHGRHK
     EISSRVKHMN N
//