ID   R2SVM6_9ENTE            Unreviewed;       550 AA.
AC   R2SVM6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Coenzyme A disulfide reductase {ECO:0000313|EMBL:EOH99290.1};
GN   ORFNames=UAW_00440 {ECO:0000313|EMBL:EOH99290.1};
OS   Enterococcus haemoperoxidus ATCC BAA-382.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1158608 {ECO:0000313|EMBL:EOH99290.1, ECO:0000313|Proteomes:UP000013858};
RN   [1] {ECO:0000313|EMBL:EOH99290.1, ECO:0000313|Proteomes:UP000013858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-382 {ECO:0000313|EMBL:EOH99290.1,
RC   ECO:0000313|Proteomes:UP000013858};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Enterococcus haemoperoxidus BAA-382.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOH99290.1}.
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DR   EMBL; AJAR01000010; EOH99290.1; -; Genomic_DNA.
DR   RefSeq; WP_010760652.1; NZ_KE136479.1.
DR   AlphaFoldDB; R2SVM6; -.
DR   STRING; 155618.RV06_GL002632; -.
DR   PATRIC; fig|1158608.3.peg.417; -.
DR   eggNOG; COG0446; Bacteria.
DR   eggNOG; COG0607; Bacteria.
DR   OrthoDB; 9802028at2; -.
DR   Proteomes; UP000013858; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd01524; RHOD_Pyr_redox; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   PANTHER; PTHR43031; FAD-DEPENDENT OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR43031:SF7; NITRIC OXIDE REDUCTASE FLRD-NAD(+) REDUCTASE; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF02852; Pyr_redox_dim; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR   SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
PE   4: Predicted;
FT   DOMAIN          461..549
FT                   /note="Rhodanese"
FT                   /evidence="ECO:0000259|PROSITE:PS50206"
SQ   SEQUENCE   550 AA;  59682 MW;  2564972CB161318E CRC64;
     MRVVIIGGVA GGMSAATRLR RLSEEIEIIV LEKGPYVSFA NCGLPYYVSG EISERSELIL
     QTPEQLKKRF NIDVYPETEA VKIDRKNKTV LTNANGKEDT ISYDKLILSP GAQPVLPTIE
     GLNEATNVYT LRNVPDVDKI VATVKNEHPK KAVVIGAGFI GLEMAENLSH LGIDVTIVEA
     APQILPPLDE EMAAFVEKEL KEKGITVYTG SGATEFKKAG KQIKLSSGET ISSDFTVLSI
     GVKPSSDLAV VADLKTGIRG GIVVDETYQT TDPDIYAVGD AIIVKQQITQ EDALILLASP
     ANRQGRQVAD VIAGVARKNQ GSIGTAIVRV FDLAAASTGL SERQLRNNNL EYKAVHTTSK
     SHAGYFPGSH PIVMKLLFHP VSGKIYGAQA IGQDGVDKRI DIIATAIKAD MTVMDLPELE
     FTYAPPFGSA KDPVNMIGYA ATNIVEGFSD TIQYYELKKA IENGAFLLDV RNPGELKSNG
     SLPQAENIPL DELRSRLTEL PSDKEIIVSC QSGQRSYLAE RILKNNDFNV KNLDGAFQLY
     STIYPQEVIK
//