ID R2SZQ4_9ENTE Unreviewed; 450 AA.
AC R2SZQ4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Branched-chain amino acid transport system carrier protein {ECO:0000256|RuleBase:RU362122};
GN ORFNames=UAW_01452 {ECO:0000313|EMBL:EOH98271.1};
OS Enterococcus haemoperoxidus ATCC BAA-382.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1158608 {ECO:0000313|EMBL:EOH98271.1, ECO:0000313|Proteomes:UP000013858};
RN [1] {ECO:0000313|EMBL:EOH98271.1, ECO:0000313|Proteomes:UP000013858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-382 {ECO:0000313|EMBL:EOH98271.1,
RC ECO:0000313|Proteomes:UP000013858};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Gilmore M.S., Lebreton F., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus haemoperoxidus BAA-382.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids. {ECO:0000256|RuleBase:RU362122}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362122};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362122}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000256|ARBA:ARBA00008540, ECO:0000256|RuleBase:RU362122}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOH98271.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJAR01000013; EOH98271.1; -; Genomic_DNA.
DR RefSeq; WP_010761658.1; NZ_KE136480.1.
DR AlphaFoldDB; R2SZQ4; -.
DR STRING; 155618.RV06_GL000081; -.
DR PATRIC; fig|1158608.3.peg.1427; -.
DR eggNOG; COG1114; Bacteria.
DR OrthoDB; 9783920at2; -.
DR Proteomes; UP000013858; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR NCBIfam; TIGR00796; livcs; 1.
DR PANTHER; PTHR30588; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR PANTHER; PTHR30588:SF0; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW ECO:0000256|RuleBase:RU362122};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362122};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362122};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362122};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362122}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 123..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 153..171
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 286..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 320..343
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 349..370
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 420..441
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
SQ SEQUENCE 450 AA; 48914 MW; FA3ED9876C2983F8 CRC64;
MTKKLSWRDY LYVGSMLFGL FFGAGNLIFP VHMGQEAGAS IFLANLGFLI TGIGLPFLGV
IAIGISKSNG VFDLATRINR RYAVAFTVLL YLTIGPFFAL PRLATTSFEI GLAPFIPSDQ
HKLILAIFSA LFFLIAWAFS RKPTKLLGYV GKFLNPLFLF LLAILILFAF LTPLGSISSA
PVAETYVANP FFKGFTEGYN TLDALASLAF GIIIVSTIRG MGVEKPNDIA KDTIKSGAIS
IVLMGIIYTL LSYMGTMSLG KFPLSENGGI ALAQIANHYL GNLGSILLAF IVILACLKTA
IGLITACSET FSELFPKGSY AFYIAAASIL PCLFANVGLT NIIQFSVPVL MFLYPLAMTL
MILVIISPLF HHRKEVYRMT TYVTLFAALL DALNSAPDFI KSNTVVTTIL KNAENYLPLF
TIGMGWVVPS IVGFIIGLIW IKVKKESVLN
//
