ID   R4GCX3_ANOCA            Unreviewed;       427 AA.
AC   R4GCX3;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=ZZ-type domain-containing protein {ECO:0000259|PROSITE:PS50135};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000023200.2, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000023200.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000023200.2};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000023200.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; R4GCX3; -.
DR   STRING; 28377.ENSACAP00000023200; -.
DR   Ensembl; ENSACAT00000030620.2; ENSACAP00000023200.2; ENSACAG00000028631.2.
DR   eggNOG; KOG4286; Eukaryota.
DR   GeneTree; ENSGT00940000162403; -.
DR   HOGENOM; CLU_027773_0_0_1; -.
DR   InParanoid; R4GCX3; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000028631; Expressed in gonad and 2 other cell types or tissues.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.60.90; -; 1.
DR   InterPro; IPR000433; Znf_ZZ.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR12268:SF18; DYSTROTELIN; 1.
DR   PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR   Pfam; PF00569; ZZ; 1.
DR   SMART; SM00291; ZnF_ZZ; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS01357; ZF_ZZ_1; 1.
DR   PROSITE; PS50135; ZF_ZZ_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00228}.
FT   DOMAIN          3..59
FT                   /note="ZZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50135"
FT   REGION          284..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          165..248
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        290..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   427 AA;  48861 MW;  EF8D42168B92BF2D CRC64;
     MVTHKVKCNV CKHFPITGLR YHCLKCLNFN LCQTCFFTGQ LCKPHKKTHP IVEHCRTVSA
     RDNIKLFSRV IRNNLLPGRC KRKEALRRKA LGLMDNRDFP TQGQPHPSSI QLVSTEDLEP
     PDLFTAEHTS NVQLNHPSDA KASQAHQKDN HGRSLDQKIT SSQILSSLEL ELAKTQESIK
     ALQNENRHLR KQLAKWKNQV QALHSAQEDR NHWFDELIVN QENLKMELQK MRIEIKTLYN
     NKSLKERNIQ HGTSHPPFKP KHMKYLKCKS APCIEKKWFL KEPPLTKNPR MPATTLQSQP
     SPHASSEVVQ HENLNRETVP LTNHSGGQKP EHSEDHFSME IKASSSHFSP PVRQTEEEEL
     QHLLTKLKNA LSFQAQPGQS CLPKDGLLST AEHVYKSFSD VISQVTLPTM KYEGSGTSPF
     LLLHCPR
//