ID R4K5V3_CLOPA Unreviewed; 110 AA.
AC R4K5V3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=HIT family hydrolase, diadenosine tetraphosphate hydrolase {ECO:0000313|EMBL:AGK97076.1};
GN ORFNames=Clopa_2199 {ECO:0000313|EMBL:AGK97076.1};
OS Clostridium pasteurianum BC1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=86416 {ECO:0000313|EMBL:AGK97076.1, ECO:0000313|Proteomes:UP000013523};
RN [1] {ECO:0000313|EMBL:AGK97076.1, ECO:0000313|Proteomes:UP000013523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1 {ECO:0000313|EMBL:AGK97076.1,
RC ECO:0000313|Proteomes:UP000013523};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Dunn J.,
RA Taghavi S., Francis A., van der Lelie D., Woyke T.;
RT "Complete sequence of chromosome of Clostridium pasteurianum BC1.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003261; AGK97076.1; -; Genomic_DNA.
DR RefSeq; WP_015615383.1; NC_021182.1.
DR AlphaFoldDB; R4K5V3; -.
DR STRING; 86416.Clopa_2199; -.
DR KEGG; cpas:Clopa_2199; -.
DR PATRIC; fig|86416.3.peg.2175; -.
DR eggNOG; COG0537; Bacteria.
DR HOGENOM; CLU_056776_8_1_9; -.
DR OrthoDB; 9784774at2; -.
DR Proteomes; UP000013523; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd01276; PKCI_related; 1.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR InterPro; IPR019808; Histidine_triad_CS.
DR InterPro; IPR001310; Histidine_triad_HIT.
DR InterPro; IPR011146; HIT-like.
DR InterPro; IPR036265; HIT-like_sf.
DR PANTHER; PTHR23089:SF33; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1; 1.
DR PANTHER; PTHR23089; HISTIDINE TRIAD HIT PROTEIN; 1.
DR Pfam; PF01230; HIT; 1.
DR PRINTS; PR00332; HISTRIAD.
DR SUPFAM; SSF54197; HIT-like; 1.
DR PROSITE; PS00892; HIT_1; 1.
DR PROSITE; PS51084; HIT_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AGK97076.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013523}.
FT DOMAIN 5..110
FT /note="HIT"
FT /evidence="ECO:0000259|PROSITE:PS51084"
FT MOTIF 98..102
FT /note="Histidine triad motif"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT ECO:0000256|PROSITE-ProRule:PRU00464"
FT ACT_SITE 100
FT /note="Tele-AMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ SEQUENCE 110 AA; 12232 MW; C3FAD248CD98E8FC CRC64;
MEDCLFCKII KGEIPCDKVY EDDKVLSFKD INPEAPVHVL TVPKKHISST NDLKAEDEEL
VGYIYTVMVK IAKQLGISEK GYRIISNCGE DAGQTVSHIH FHLLGGGKLD
//
