ID R4LYE9_MYCTX Unreviewed; 110 AA.
AC R4LYE9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=CobW/HypB/UreG nucleotide-binding domain-containing protein {ECO:0000259|Pfam:PF02492};
GN ORFNames=I917_19945 {ECO:0000313|EMBL:AGL24434.1};
OS Mycobacterium tuberculosis str. Haarlem/NITR202.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=1304279 {ECO:0000313|EMBL:AGL24434.1, ECO:0000313|Proteomes:UP000013563};
RN [1] {ECO:0000313|EMBL:AGL24434.1, ECO:0000313|Proteomes:UP000013563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Haarlem/NITR202 {ECO:0000313|EMBL:AGL24434.1,
RC ECO:0000313|Proteomes:UP000013563};
RX PubMed=23788533;
RA Narayanan S., Deshpande U.;
RT "Whole-Genome Sequences of Four Clinical Isolates of Mycobacterium
RT tuberculosis from Tamil Nadu, South India.";
RL Genome Announc. 1:e00186-13(2013).
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM
CC subfamily. {ECO:0000256|ARBA:ARBA00006211}.
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DR EMBL; CP004886; AGL24434.1; -; Genomic_DNA.
DR AlphaFoldDB; R4LYE9; -.
DR SMR; R4LYE9; -.
DR KEGG; mtuh:I917_19945; -.
DR PATRIC; fig|1304279.3.peg.3359; -.
DR HOGENOM; CLU_173251_0_0_11; -.
DR BioCyc; MTUB1304279:G13AB-2699-MONOMER; -.
DR Proteomes; UP000013563; Chromosome.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR004392; Hyd_mat_HypB.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR30134:SF2; HYDROGENASE MATURATION FACTOR HYPB; 1.
DR PANTHER; PTHR30134; HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE; 1.
DR Pfam; PF02492; cobW; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 32..91
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
SQ SEQUENCE 110 AA; 11647 MW; 8ECFBD9D24BD543A CRC64;
MLEKIFAEND VRANVNRAAF ENNGIRALDL MSSPGSGKTT VLGAALDEHA DQFAIGVIEG
DITTDLDAAN GRGTQVSLLN NQHGFCAECH LDAPMVNRAL AGAPDGVRRR
//
