ID R4SSB9_9PSEU Unreviewed; 205 AA.
AC R4SSB9; A0A1H2HF25;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=DNA-binding transcriptional regulator, AcrR family {ECO:0000313|EMBL:SDU30339.1};
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:AGM05470.1};
GN ORFNames=AORI_2884 {ECO:0000313|EMBL:AGM05470.1}, SAMN04489733_2866
GN {ECO:0000313|EMBL:SDU30339.1};
OS Amycolatopsis keratiniphila.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
OX NCBI_TaxID=129921 {ECO:0000313|EMBL:AGM05470.1, ECO:0000313|Proteomes:UP000013968};
RN [1] {ECO:0000313|EMBL:AGM05470.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM05470.1};
RA Xu L., Zhao W., Ge M., Zhao G.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGM05470.1, ECO:0000313|Proteomes:UP000013968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM05470.1,
RC ECO:0000313|Proteomes:UP000013968};
RX PubMed=23627759; DOI=10.1186/1471-2164-14-289;
RA Tang B., Wang Q., Yang M., Xie F., Zhu Y., Zhuo Y., Wang S., Gao H.,
RA Ding X., Zhang L., Zhao G., Zheng H.;
RT "ContigScape: a Cytoscape plugin facilitating microbial genome gap
RT closing.";
RL BMC Genomics 14:289-289(2013).
RN [3] {ECO:0000313|EMBL:SDU30339.1, ECO:0000313|Proteomes:UP000182988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH 1893 {ECO:0000313|EMBL:SDU30339.1,
RC ECO:0000313|Proteomes:UP000182988};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003410; AGM05470.1; -; Genomic_DNA.
DR EMBL; LT629789; SDU30339.1; -; Genomic_DNA.
DR RefSeq; WP_016333237.1; NZ_LT629789.1.
DR AlphaFoldDB; R4SSB9; -.
DR KEGG; aoi:AORI_2884; -.
DR PATRIC; fig|1156913.3.peg.2956; -.
DR HOGENOM; CLU_069356_12_4_11; -.
DR Proteomes; UP000013968; Chromosome.
DR Proteomes; UP000182988; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF253; HTH-TYPE TRANSCRIPTIONAL REPRESSOR KSTR2; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000013968};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..77
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 40..59
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 205 AA; 23116 MW; 3CF3AC86072EB880 CRC64;
MTRATTRKAE AGGEDQAAVP RRLLSHATKL FAKKGFDRTS VQEIVEAAGV TKGAMYHYFG
SKDDLLYEIY ARVLRSQTEQ LEKVASSEAP LRERLRSAAS DVIVSTIDNL DDNTIFMQSM
HQLSVEKQKA VRAERRKYHE RFRTLIEEGQ ESGEFRGDKP ADVIVDFFFG SVHHLGSWYR
RGGALSARQI GDHFADLLLA ALRPE
//
