ID R4T5I7_9PSEU Unreviewed; 470 AA.
AC R4T5I7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Fatty acid CoA ligase {ECO:0000313|EMBL:AGM06287.1};
GN ORFNames=AORI_3702 {ECO:0000313|EMBL:AGM06287.1};
OS Amycolatopsis keratiniphila.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
OX NCBI_TaxID=129921 {ECO:0000313|EMBL:AGM06287.1, ECO:0000313|Proteomes:UP000013968};
RN [1] {ECO:0000313|EMBL:AGM06287.1, ECO:0000313|Proteomes:UP000013968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM06287.1,
RC ECO:0000313|Proteomes:UP000013968};
RX PubMed=23627759; DOI=10.1186/1471-2164-14-289;
RA Tang B., Wang Q., Yang M., Xie F., Zhu Y., Zhuo Y., Wang S., Gao H.,
RA Ding X., Zhang L., Zhao G., Zheng H.;
RT "ContigScape: a Cytoscape plugin facilitating microbial genome gap
RT closing.";
RL BMC Genomics 14:289-289(2013).
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DR EMBL; CP003410; AGM06287.1; -; Genomic_DNA.
DR RefSeq; WP_016334051.1; NC_021252.1.
DR AlphaFoldDB; R4T5I7; -.
DR KEGG; aoi:AORI_3702; -.
DR PATRIC; fig|1156913.3.peg.3785; -.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000013968; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AGM06287.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013968}.
FT DOMAIN 17..327
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 375..451
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 470 AA; 49478 MW; 5322E748B2C4A0BB CRC64;
MESLFLTRVL DALRSGGDEV LFVQDGVETG YGQALELVRR MYAGLPEGGV VAIDAGNRPE
TVLLQIAAQL RGSTVLLVAA SASAPDRLAA VEAAGVTTLV AEHAADWPDG VTTLDELVDR
DGADPARLPG SVTVVFPTGG TTGTPKLIRH SGIYDGMAHI FAPDPAGPGR TLLIAPMTHM
TGNATVLGAI LRRESVVLLR GFDAGAVLDA IAEHRITSLS LTPARLAAVL DHPAMTSTDV
GSVRQLSLGA APLPPRRLAQ ALDVFGPVVG QGYGLTEAPM IASISAAELD GRPERLESVG
RIVPGMEARI DEGEVLVRGL SMMDGYHGSV PIGDGWLRTG DLGRFDDEGY LYLLDRANDV
IITGEHGTKV YSTVVENALA RHPLIRSVAV FGVPGDDGEG ERVHAVVVPV APGALSADEV
RAHARDFFGR EHFVPSDVDF TGALPLTAIG KIDKRALRAP FWSGHRRRIA
//
