ID R4T971_9PSEU Unreviewed; 475 AA.
AC R4T971; A0A1H2KKY0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=XRE family transcriptional regulator {ECO:0000313|EMBL:AGM08861.1};
GN ORFNames=AORI_6278 {ECO:0000313|EMBL:AGM08861.1}, SAMN04489733_8414
GN {ECO:0000313|EMBL:SDU68995.1};
OS Amycolatopsis keratiniphila.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
OX NCBI_TaxID=129921 {ECO:0000313|EMBL:AGM08861.1, ECO:0000313|Proteomes:UP000013968};
RN [1] {ECO:0000313|EMBL:AGM08861.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM08861.1};
RA Xu L., Zhao W., Ge M., Zhao G.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGM08861.1, ECO:0000313|Proteomes:UP000013968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM08861.1,
RC ECO:0000313|Proteomes:UP000013968};
RX PubMed=23627759; DOI=10.1186/1471-2164-14-289;
RA Tang B., Wang Q., Yang M., Xie F., Zhu Y., Zhuo Y., Wang S., Gao H.,
RA Ding X., Zhang L., Zhao G., Zheng H.;
RT "ContigScape: a Cytoscape plugin facilitating microbial genome gap
RT closing.";
RL BMC Genomics 14:289-289(2013).
RN [3] {ECO:0000313|EMBL:SDU68995.1, ECO:0000313|Proteomes:UP000182988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH 1893 {ECO:0000313|EMBL:SDU68995.1,
RC ECO:0000313|Proteomes:UP000182988};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003410; AGM08861.1; -; Genomic_DNA.
DR EMBL; LT629789; SDU68995.1; -; Genomic_DNA.
DR RefSeq; WP_016336577.1; NZ_LT629789.1.
DR AlphaFoldDB; R4T971; -.
DR KEGG; aoi:AORI_6278; -.
DR PATRIC; fig|1156913.3.peg.6405; -.
DR HOGENOM; CLU_046383_0_0_11; -.
DR Proteomes; UP000013968; Chromosome.
DR Proteomes; UP000182988; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR026281; HTH_RamB.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR018653; ScfR_C.
DR PANTHER; PTHR46797; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR46797:SF23; HTH-TYPE TRANSCRIPTIONAL REGULATOR PRPR; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR Pfam; PF09856; ScfRs; 1.
DR PIRSF; PIRSF019251; Rv0465c; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000013968};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..64
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 475 AA; 52421 MW; 4F877B4D5BB734ED CRC64;
MDKTFAGAKL RHLRESRSMS QADLARVLEI SPSYLNQIEH NSRPLTVPVL LRITQAFGVD
TEFFANNDTA RLVADVKEAL LDEVLGVDVT NSELNDLATN LPTIAQALVK LHRSYRNAVE
NTAALTTENG LGLHGSAATA LPHEEVRDFF YERENYVAEL DERAERMAHD IPLQRGQVLA
ALKETLIQRY GVDVTSEGID EANGEQHRYE PGPRVLRLAP SLRVGQQAFR MASQIALLEY
DDLITELADS WAFSGPAARS LARVGLANYF AGALILPYGP FLSTAERFRY DIERLCDHFG
VGFETVCHRL STLQRPKNRG VPFSFVRVDR AGNMSKRQSA AGFHFSRVGG ACPLWNIYEA
FTQPGKILTQ IATLPDGKSY FWVARTVSRN IGGYGSPGKT FTVGLGCELR HAKRLIYSTG
LDLDDRAAAT PIGMGCKVCE RPACSQRAFP TIGKQLTVDE NTSTFVPYPA VPKSP
//
