ID R4TAV5_9PSEU Unreviewed; 271 AA.
AC R4TAV5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Putative hemolysin {ECO:0000313|EMBL:AGM07628.1};
GN Name=tlyA {ECO:0000313|EMBL:AGM07628.1};
GN ORFNames=AORI_5044 {ECO:0000313|EMBL:AGM07628.1};
OS Amycolatopsis keratiniphila.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
OX NCBI_TaxID=129921 {ECO:0000313|EMBL:AGM07628.1, ECO:0000313|Proteomes:UP000013968};
RN [1] {ECO:0000313|EMBL:AGM07628.1, ECO:0000313|Proteomes:UP000013968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM07628.1,
RC ECO:0000313|Proteomes:UP000013968};
RX PubMed=23627759; DOI=10.1186/1471-2164-14-289;
RA Tang B., Wang Q., Yang M., Xie F., Zhu Y., Zhuo Y., Wang S., Gao H.,
RA Ding X., Zhang L., Zhao G., Zheng H.;
RT "ContigScape: a Cytoscape plugin facilitating microbial genome gap
RT closing.";
RL BMC Genomics 14:289-289(2013).
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
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DR EMBL; CP003410; AGM07628.1; -; Genomic_DNA.
DR RefSeq; WP_016335374.1; NC_021252.1.
DR AlphaFoldDB; R4TAV5; -.
DR KEGG; aoi:AORI_5044; -.
DR PATRIC; fig|1156913.3.peg.5132; -.
DR HOGENOM; CLU_058015_1_0_11; -.
DR Proteomes; UP000013968; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013968};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 5..71
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 271 AA; 28446 MW; 4E2F9812A4C92051 CRC64;
MPKRARLDAE LVRRGLARSR EQASTLIAEG KVTVRGMVAT KPATGVESGA PIVVRDGDDP
GWASRGAHKL LGALEVFTPQ GLSTEGKRCL DAGASTGGFT DVLLRNGAAT VIAADVGRGL
LDWRLRTDDR VVVLDKTNVR NLTPEDLGGQ VDLVVGDLSF ISLKLVLPAL AACARDGADL
VPMVKPQFEV GKDRLGSGGV VRDPELRVES VLGVLAEAEK LDLSLRGVVA SPLPGPSGNV
EYFVWLTRGA GETAGTDAER LVRTAVLEGP Q
//
