ID R4TGK2_9PSEU Unreviewed; 999 AA.
AC R4TGK2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=SARP family transcriptional regulator {ECO:0000313|EMBL:AGM09403.1};
GN ORFNames=AORI_6821 {ECO:0000313|EMBL:AGM09403.1};
OS Amycolatopsis keratiniphila.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis japonica group.
OX NCBI_TaxID=129921 {ECO:0000313|EMBL:AGM09403.1, ECO:0000313|Proteomes:UP000013968};
RN [1] {ECO:0000313|EMBL:AGM09403.1, ECO:0000313|Proteomes:UP000013968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB10007 {ECO:0000313|EMBL:AGM09403.1,
RC ECO:0000313|Proteomes:UP000013968};
RX PubMed=23627759; DOI=10.1186/1471-2164-14-289;
RA Tang B., Wang Q., Yang M., Xie F., Zhu Y., Zhuo Y., Wang S., Gao H.,
RA Ding X., Zhang L., Zhao G., Zheng H.;
RT "ContigScape: a Cytoscape plugin facilitating microbial genome gap
RT closing.";
RL BMC Genomics 14:289-289(2013).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003410; AGM09403.1; -; Genomic_DNA.
DR RefSeq; WP_016337104.1; NC_021252.1.
DR AlphaFoldDB; R4TGK2; -.
DR KEGG; aoi:AORI_6821; -.
DR PATRIC; fig|1156913.3.peg.6957; -.
DR HOGENOM; CLU_004665_2_0_11; -.
DR Proteomes; UP000013968; Chromosome.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000013968}.
FT DOMAIN 17..89
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 96..240
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 107550 MW; 5F39DF20D533AA13 CRC64;
MPRFGVLGPL TIEDPPGRRT TPRGDHQRAL LAVLLLNANS SVPVDALVET LWPDTPPKSY
SSNLHTYVSR LRARFEGLEI QRDPHGYRLV VEPADLDLLS FREAAAAGKA AARAGDPATA
AGHYRRALAE WRGPVLSGLH IPRLDADVAR LESERLAAFE DCVDAELSDG RHGELTGELQ
AMITEHPLRE RLAAQLMIAL HRAGRQADSL AVHRDLRATL VEELGVEPGA EVRRVHAAVL
RGEDPVPSAK TAPIFPICQL PPDIADLAGR ESEIAKLSGL LGDGTGVPVA VITGEPGAGK
STLAVATAHR LRRSFPDGQL FVPLAGASDP RDLSDVLGDL LRALGVTGPA IPDDVEARAA
VYRGRLADRR VLVVLDDAAS PEQVRALLPG TPGTAVLITS RRRLSGLAGA DRLPLAPLSG
AEAMTLLARL AGPDRVGAER ADAERIAKAC GNLPLALRIA GSRLAMRPGL PLGKLAGRLE
DEVSRLDELQ VSDLQVRGSI ALSYRALSPA ARRAFRLIGR CRTLDLPAWA VTTLIDDEGA
DEAIDELVEA SLLEATGLDP TGEQRFRVHD LVRVFATELG RELETRDERV ATVAKVSDAA
LCLADTAARR LPRTVPMPLS DHDVPAQPLE AELVERLLRD PGTWFSVERA NLVSAVSSLC
AVGWRRKALR ILERLSAYLY LHSHYTDMRT AYETLRDAAR EAGDRRIAVI AEANLAVLLH
VRGEYERAAE GYRACSKELA ELGDLATRAW VETNLAHCLV GLGRAGESLH AATQAREMST
VEDSGTHARR AESAALHRLG KISEALEIDR RILAQARESA DDRQLGVALQ GLSWSLMLDG
RQEEALATIE ESVRVLRRTT AKSALAKSLR TQGAILAGAG RRDGAVKAYE NARRLAGALE
ERPRELSCTR AIAASWIGDG RADRAIPVLR RCLDEFRAMG GKPATGLTLH VLRRAYEAVG
ETEAAEAAGE EAKRLEVPHD ANASTLVRLL LSLTEPAPA
//
