ID R4WPD2_9BURK Unreviewed; 659 AA.
AC R4WPD2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=transketolase {ECO:0000256|ARBA:ARBA00013152};
DE EC=2.2.1.1 {ECO:0000256|ARBA:ARBA00013152};
GN ORFNames=BRPE64_CCDS04500 {ECO:0000313|EMBL:BAN26533.1};
OS Caballeronia insecticola.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=758793 {ECO:0000313|EMBL:BAN26533.1, ECO:0000313|Proteomes:UP000013966};
RN [1] {ECO:0000313|Proteomes:UP000013966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23833137; DOI=10.1128/genomeA.00441-13;
RA Shibata T.F., Maeda T., Nikoh N., Yamaguchi K., Oshima K., Hattori M.,
RA Nishiyama T., Hasebe M., Fukatsu T., Kikuchi Y., Shigenobu S.;
RT "Complete Genome Sequence of Burkholderia sp. Strain RPE64, Bacterial
RT Symbiont of the Bean Bug Riptortus pedestris.";
RL Genome Announc. 1:340-344(2013).
RN [2] {ECO:0000313|EMBL:BAN26533.1, ECO:0000313|Proteomes:UP000013966}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RPE64 {ECO:0000313|EMBL:BAN26533.1};
RX PubMed=29863457; DOI=10.1099/ijsem.0.002848;
RA Takeshita K., Tamaki H., Ohbayashi T., Meng X.-Y., Sone T., Mitani Y.,
RA Peeters C., Kikuchi Y., Vandamme P.;
RT "Burkholderia insecticola sp. nov., a gut symbiotic bacterium of the bean
RT bug Riptortus pedestris.";
RL Int. J. Syst. Evol. Microbiol. 68:2370-2374(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate =
CC aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate;
CC Xref=Rhea:RHEA:10508, ChEBI:CHEBI:57483, ChEBI:CHEBI:57737,
CC ChEBI:CHEBI:58273, ChEBI:CHEBI:59776; EC=2.2.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001027};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
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DR EMBL; AP013060; BAN26533.1; -; Genomic_DNA.
DR RefSeq; WP_016347242.1; NC_021288.1.
DR AlphaFoldDB; R4WPD2; -.
DR STRING; 758793.BRPE64_CCDS04500; -.
DR KEGG; buo:BRPE64_CCDS04500; -.
DR PATRIC; fig|758793.3.peg.4766; -.
DR HOGENOM; CLU_009227_0_0_4; -.
DR OrthoDB; 8732661at2; -.
DR Proteomes; UP000013966; Chromosome 3.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR CDD; cd02012; TPP_TK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR005478; Transketolase_bac-like.
DR InterPro; IPR033248; Transketolase_C.
DR InterPro; IPR033247; Transketolase_fam.
DR InterPro; IPR005474; Transketolase_N.
DR NCBIfam; TIGR00232; tktlase_bact; 1.
DR PANTHER; PTHR43522; TRANSKETOLASE; 1.
DR PANTHER; PTHR43522:SF2; TRANSKETOLASE 1-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 351..521
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 659 AA; 71599 MW; 7FBF7AC66BBBB7DB CRC64;
MSSIDTQPLS NAIRFLAIDA IVRAGEGHQG VPLGMAEIAT ALFTRHMKFN PADPQWPDRD
RFVLSNGHGS MLLYALLHLT GYANFGIEQI RTFRDMGSHC EGHPEFDTAS GIEVTTGPLG
QGIANAFGMA VAEAYLNAKF GAGIVDHYTY AFVGDGCLQE GVGQEMISLA GHLKLGKLIL
CWDDNQITDD GSTTLSISEN VSERFRVAGW HVIEVDGHDL EAVSNALAQA KADPRPSMLA
CRTTIARGIA RLQGQRGGHS GRLFDKDSDA ARTSMNWPHA PFEIPDDVLH AWREAGRRSE
EEYRAWRERV ASLPAEARAE LERIQAGELP EGWRRTLDAY KRDAPARDDT PGGIMISAEI
NDLLANALPE RMVACADLEA PTSHKRSLRA FTAEDRGGAY VHCGVREHVM GAMANGMAAH
GGVIPLTVTY LAFSDYERPA MRMAALMGLP VKFVFSHDSI GVGKNGPTHQ PVEILASLRA
MPNMYVFRPA DAVEAAECWM LAYDRKHGPS TMVFARQALP LVRTQHEDEN RSARGGYVLA
EAEGGARRVT LIATGSEVAC ALAAREQLQA AGIATAVVSM PCCERFDEQD AAYRSSVLGA
DTVRVVVEAA VRFGWDRVIG ERGGFVGMKG FGASGPAEAL YEHFGITPRH IVEEVKRHL
//
